2019 Department of Internal Medicine Annual Research Symposium
 
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Presentation
- Mirette Habib, BS - Forced Vital Capacity Trajectories for System Sclerosis-Associated Interstitial Lung Disease: Analysis from the University of Michigan Scleroderma Cohort
Posters
- Sara Jaafar, MDÂ - Impact of 6th World Symposium on Pulmonary Hypertension on the Definition of Pulmonary Arterial Hypertension: Analysis of Two Scleroderma Cohorts
- Sara Jaafar, MDÂ - Characteristics of Early Disease in Systemic Sclerosis-Associated Interstitial Lung Disease: Analysis from UM Scleroderma Cohort
- Vivek Nagaraja, MBBSÂ - Multicenter Double-Blind, Proof-of-Concept, Randomized Placebo-Controlled Trial of Riociguat in Systemic Sclerosis-Associated Digital Ulcers
- Vivek Nagaraja, MBBS - Use of Handheld Device to Enhance Patient Reported Outcome Measures (PROMIS®) Data Collection in Rheumatology Clinics
- David Roofeh, MDÂ - Exemplar-Based Classification of Subsets in Systemic Sclerosis-Associated ILD
2019 ACR Annual Meeting
- Dinesh Khanna, MD, MSc, et al. Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis - Results of Phase I/II Investigator-Initiated, Double-Blind Randomized Placebo-Controlled Trial
- Dinesh Khanna, MD, MSc, et al. Responsiveness to Change of the Modified Rodnan Skin Score in a Phase I/II Double-Blind Randomized Placebo-Controlled Trial
- Vivek Nagaraja, MD, et al. Multicenter Double-Blind, Proof-of-Concept, Randomized Placebo-Controlled Trial of Riociguat in Systemic Sclerosis-Associated Digital Ulcers
- David Roofeh, MD, et al. Defining Subsets in Systemic Sclerosis - Interstitial Lung Disease
- Sara Jaafar, MD, et al. Relationship Between High-Resolution Computer Tomography and FVC% Predicted for Classification of Pulmonary Hypertension in Systemic Sclerosis
- Mirette Habib, BS, et al. Forced Vital Capacity Trajectories for Systemic Sclerosis-Associated Interstitial Lung Disease: Analysis from the University of Michigan Scleroderma Cohort
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2018 ACR Annual Meeting
- Kate Homer, Benjamin Brennan, Shervin Assassi, Elana Bernstein, Flavia Castelino, Robyn Domsic, Jessica Gordon, Faye Hant, Monique Hinchcliff, Ami Shah, Victoria K. Shanmugam, Virginia Steen, Veronica J. Berrocal, Melanie Hemmrich, Tracy Frech, and Dinesh Khanna. Progressive Skin Fibrosis, Internal Organ Involvement and All - Cause Mortality in an Early Systemic Sclerosis US Multicenter Registry. Abstract, 2018 ACR Annual Meeting, Chicago, IL. Poster presentation.
- Kate Homer, Jeffery Warren, Dmitry Karayev, Puja Khanna, Amber Young, Vivek Nagaraja, Allan Metzger, Dinesh Khanna. Performance of Anti-topoisomerase I Antibody Testing by Multiple-bead, Enzyme-linked Immunosorbent Assay, and Immunodiffusion in a University Setting. Abstract, 2018 ACR Annual Meeting, Chicago, IL. Poster presentation.
- Dinesh Khanna, Cathie Spino. Evaluation of American College of Rheumatology Provisional Composite Response Index in Systemic Sclerosis in a Phase II Trial of Abatacept vs. Placebo. Abstract, 2018 ACR Annual Meeting, Chicago, IL. Poster presentation.
- Vivek Nagaraja, Vladimir Ognenovski, Victoria Elder, Steve Bearinger, Dinesh Khanna. Use of Handheld Device to Enhance Patient Reported Outcome Measure Data Collection in an Academic Rheumatology Practice. Abstract, 2018 ACR Annual Meeting, Chicago, IL. Poster presentation.
- Vivek Nagaraja, John H Powers, Celia J.F. Lin, Benjamin Brennan, Veronica J. Berrocal, Dinesh Khanna. Patient-level Evaluation of Components of the ACR Combined Response Index in Systemic Sclerosis (CRISS) Using Patient-Reported Anchor. Abstract, 2018 ACR Annual Meeting, Chicago, IL. Poster presentation.
- Cathie Spino, Robert A Parker, Dinesh Khanna. Rescuing Standard Analyses of Immunosuppressive Rescue Therapy in Randomized Controlled Trials: Alternative Approaches in a Sclerosis in a Clinical Trial. Abstract, 2018 ACR Annual Meeting, Chicago, IL. Poster presentation.
2015 ACR Annual Meeting
- Volkmann ER, Roth M, Elashoff R, Clements PJ, Furst DE, Khanna D, Goldin J, Tashkin D. Safety and Tolerability of Cyclophosphamide Versus Mycophenolate for Systemic Sclerosis-Related Interstitial Lung Disease. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Gordon JK, Berrocal VJ, Girish G, Zhang M, Hatzis C, Assassi S, Bernstein EJ, Domsic RT, Hant FN, Hinchcliff ME, Schiopu E, Steen VD, Frech TM, Khanna D. Reliability and Validity of the Total Joint Count and Swollen Joint Count in Early Diffuse Systemic Sclerosis. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Khanna D, Albera C, Fischer A, Seibold JR, Khalidi NA, Raghu G, Chung L, Schiopu E, Chen D, Gorina E. Safety and Tolerability of Pirfenidone in Patients with Systemic Sclerosis Interstitial Lung Disease. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Clements PJ, Tashkin D, Roth M, Khanna D, Furst DE, Tseng CH, Volkmann ER, Elashoff R. The Scleroderma Lung Study II (SLS II) Shows That Both Oral Cyclophosphamide (CYC) and Mycophenolate Mofitil (MMF) Are Efficacious in Treating Progressive Interstitial Lung Disease (ILD) in Patients with Systemic Sclerosis (SSc). Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Nagaraja V, Visovatti SH, Gladue H, Berrocal VJ, Serrano J, McLaughlin V, Khanna D. Screening Algorithm for Pulmonary Hypertension in Systemic Sclerosis – Comparison of Predictive Accuracy of Three Algorithms. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Kwakkenbos L, Thombs BD, Bartlett SJ, Carrier ME, Hudson M, Mouthon L, Malcarne VL, Sauvé M, Khanna D. Construct Validity of the Promis-29 in Systemic Sclerosis: Results from the Scleroderma Patient-Centered Intervention Network (SPIN) Cohort. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- MartÃn J, Carmona FD, Fernández-Aranguren T, Serrano-Fernández A, Onat AM, Robledo G, Raya E, Direskeneli H, Sawalha AH, Yavuz S. Evaluation of Systemic Sclerosis Risk Genes in the Turkish Population. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Domsic RT, Khanna D, Lucas M, Steen VD, Furst DE, Lafyatis R, Medsger TA Jr. The Potential Effect on Recruitment of Restricting Skin Scores Eligibility Criteria in Early Diffuse Scleroderma Trials. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Gordon JK, Berrocal VJ, Assassi S, Bernstein EJ, Domsic RT, Hant FN, Hinchcliff ME, Schiopu E, Steen VD, Frech TM, Khanna D. Inter and Intrarater Reliability of the Modified Rodnan Skin Score in Early Diffuse Systemic Sclerosis. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Khanna D, Allanore Y, Denton CP, Matucci-Cerinic M, Pope JE, Hinzmann B, Briody S, de Oliveira Pena J, Distler O. Patient Perception of Disease Burden in Diffuse Cutaneous Systemic Sclerosis. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Tsou PS, Amin MA, Schiopu E, Fox DA, Khanna D, Sawalha AH. Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis Via Repressing Pro-Angiogenic Factors. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- Johnson S, Soowamber M, Fransen J, Khanna D, van den Hoogen FHJ, Baron M, Matucci Cerinic M, Denton CP, Medsger TA Jr., Carreira PE, Riemekasten G, Distler JH, Gabrielli A, Steen VD, Chung L, Silver R, Varga J, Müller-Ladner U, Vonk MC, Walker UA, Wollheim F, Herrick AL, Furst DE, Czirjak L, Kowal-Bielecka O, Del Galdo F, Cutolo M, Hunzelmann N, Murray C, Foeldvari I, Mouthon L, Damjanov N, Kahaleh B, Frech TM, Assassi S, Saketkoo LA, Pope JE. There Is a Need for New Systemic Sclerosis Subset Criteria: A Content Analytic Approach. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
- McCoy SS, Reed TJ, Tsou PS, Khanna D, Kahlenberg JM, Berthier CC. Scleroderma Keratinocytes Promote Fibroblast Activation Independent of TGF-ß. Abstract, 2015 ACR Annual Meeting, San Francisco, CA. Poster presentation.
2012 ACR Annual Meeting
- Pope JE, Khanna D, Fransen J, Johnson SR, Tyndall AG, Matucci-Cerinic M, Naden RP, van den Hoogen FHJ and ACR/EULAR Classification Criteria for Systemic Sclerosis. Classification Criteria for Systemic Sclerosis: Preliminary Results. Abstract, 2012 ACR Annual Meeting, Late Breaking Abstracts Poster Session.
2011 ACR Annual Meeting
- Khanna D, Seibold J, Merkel P, Mayes MD, Phillips K, Simms RW, Assassi S, Clements PJ, Furst DE. Construct Validity of the Saint George’s Respiratory Questionnaire in An Observational Cohort of Patients with Early Diffuse Systemic Sclerosis. Abstract, ACR 2011 Meeting Chicago, IL. Poster Presentation.
- Khanna D, Forsythe A, Khanna P. Patient Management/Treatment and Outcomes of Gout Between Primary Care Physicians and Rheumatologists: A Chart Review of 1,039 Patients with Gout In the United States. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Khanna D, Poiraudeau S, Gelhorn H, Hunsche E, Papadakis K, Perchenet L, Mattera MS, Vernon M, Mouthon L. Development and Content Validity of the Hand Disability in Systemic Sclerosis—Digital Ulcers (HDISS-DU) Scale. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Khanna P, Tausche AK, Forsythe A, Goren A, Khanna D. Gout Patient Burden Associated with Flares, Tophi, and Awareness of Uric Acid Levels in US and EU. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Khanna P, Beaton CA, Persselin JE, Hays RD, Furst DE, Paulus HE, Terkeltaub R, Maranian P, Khanna D. Impact of Acute Gout Flares on Health Related Quality of Life (HRQOL) and Productivity in Patients with Chronic Gout. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Bae S, Allanore Y, Furst DE, Bodukam V, Coustet B, Morgaceva O, Paul Maranian P, Khanna D. Associations Between the UCLA SCTC GIT 2.0 Vs. Objective Tests of Upper Gastrointestinal Involvement in Systemic Sclerosis. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Khanna P, Hirsch J, Lee SJ, Terkeltaub R, Singh J, Kavanaugh AF, Sarkin A, Khanna D. Gout Characteristics, Health-Related Quality of Life and Health Care Utilization: Caucasians Vs. Non-Caucasians In An Observational Cohort of Patients with Gout. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Khanna P, Singh MK, FitzGerald JD, Bae S, Prakash S, Kaldas M, Gogia M, Maranian P, Terkeltaub R, Khanna D. Pharmacological Treatment of Acute Gout: A Systematic Review. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Khanna P, Singh MK, Bae S, FitzGerald JD, Prakash S, Kaldas M, Gogia M, Maranian P, Terkeltaub R, Khanna D. Oral Urate Lowering Therapies in Chronic Gout: A Systematic Review and Meta-Analysis. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Johnson SR, Fransen J, Khanna D, Medsger TA, Peschken CA, Carreira P, Riemekasten G, Tyndall AG, Matucci-Cerinic M, Baron M, Van den Hoogen F, Pope JE. Validation of Potential Classification Criteria for Systemic Sclerosis. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Au KM, Khanna D, Divekar AA, Singh RR, Kaplan MJ, McMahon MA, Furst DE, Ragavendra N, Maranian P, Zhao W. Atherosclerosis Biomarkers in Systemic Sclerosis- A Multiplex Analysis. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Kushi J, Csuka ME, Hummers LK, Wigley FM, Hsu VM, Khanna D, Molitor JA, Steen VD. Elevated Pulmonary Vascular Resistance At Rest Is Associated with Exercise Pulmonary Arterial Hypertension in Systemic Sclerosis Patients without Pulmonary Hypertension Hemodynamics At Rest. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Ghrenassia E, Avouac J, Derk CT, Airo P, Khanna D, Berezne A, Tiev K, Ingegnoli F,Rosato E, Caramaschi P, Hesselstrand R, Riccieri V, Bae S, Steen VD, Allanore Y. Watermelon Stomach in Systemic Sclerosis: A EUSTAR Case-Control Study. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Saketkoo LA, Huscher D, Khanna D, Dellaripa PF, Flaherty K, Matteson EL, Oddis CV, Phillips K, Wells AU, Denton CP, Distler O, Kowal-Bielecka OM, Pittrow D, Christmann R, Sandorfi N, Strand V,Brown KK Seibold JR. Developing a Disease Activity and Therapeutic Response Index in Connective Tissue Disease Related Interstitial Lung Disease: Initial Results of a Delphi Exercise. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Gordon JK, Doobay K, Horn E, Bolster MB, Shapiro LS, Khanna D, Frech TM, Fields K, Derk CT, Hummers LK, Mayes MD, Steen VD. Clinical and Hemodynamic Features of Scleroderma Patients with Pulmonary Venous Hypertension Versus Pulmonary Arterial Hypertension. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Sharif R, Mayes MD, Tan FK, Gorlova O, Hummers LK, Shah AA, Furst DE, Khanna D, Martin J, Bossini-Castillo L, Gonzalez EB, Draeger HT, Ying J, Agarwal SK, Arnett FC, Wigley FM, Assassi S. A Functional IRF5 Variant Predicts Prognosis in Patients with Systemic Sclerosis. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
- Seibold JR, Wigley FM, Schiopu E, Denton CD, Silver RM, Steen VD, Medsger TA, Mayes MD, Chatterjee S, Chung L, Csuka ME, Khanna D, Frech TM, Molitor JA, Rothfield NF, Herrick AL, Simms RW, Pope JE, Rollins KD, Arneson C, Wade M. Digital Ischemic Ulcers in Scleroderma Treated with Oral Treprostinil Diethanolamine: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. Abstract, ACR 2011 Meeting Chicago, IL. Poster presentation.
2009 ACR Annual Meeting
- Wangkaew S, Impens AJ, Rubenfire M, Schiopu E, McLaughlin VV, Montgomery DG, Seibold JR. Correlation between submaximal exercise testing and right heart catheterization in patients with systemic sclerosis (SSc). Abstract, ACR National Meeting, 2009.
- Impens AJ, Hinchcliff ME, Hummers LK, Mayes MM, Derk CT, Shapiro LS, Domsic RT, Segal BM, Goldberg AZ, Alkassab F, Steen VD, and the PHAROS Investigators. Pulmonary hypertension assessment and recognition of outcomes in scleroderma (PHAROS): Utility of six minute walk test. Abstract, ACR National Meeting, 2009.
- Mahmood F, Impens AJ, Schiopu E, Phillips K, Lowe L, Olsen S, Seibold JR. Clinical and histopathologic comparison of generalized subcutaneous morphea (GSM) with eosinophilic fasciitis (EF). Abstract, ACR National Meeting, 2009.
2008 ACR Annual Meeting
- Seibold JR, Denton CP, Distler O, Grnig E, McLaughlin V, Müller-Ladner U, Pope J, Vonk M, Coghlan G. The DETECT study: A two-stage, prospective, observational, cohort study in scleroderma patients to evaluate screening tests and the incidence of pulmonary arterial hypertension and pulmonary hypertension. Abstract, ACR National Meeting, 2008.
- Chan KM, Tishkowski E, Impens AJ, Ojo T, McLaughlin VV, Seibold JR. Doppler echocardiography overestimates pulmonary hypertension in patients with scleroderma interstitial lung disease. Abstract, ACR National Meeting, 2008.
- Impens AJ, Wangkaew S, Rubenfire M, McLaughlin VV, Montgomery DG, Seibold JR. Correlations of 6-minute walk distance (6MWD) with subjective measures of dyspnea in systemic sclerosis (SSc) patients. Abstract, ACR National Meeting, 2008.
- Hou Y, Rabquer BJ, Jaffe ML, Del Galdo F, Jimenez SA, Haines III GK, Seibold JR, Barr WG, Massa MC, Koch AE. Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion. Abstract, ACR National Meeting, 2008.
- Rabquer BJ, Hou Y, Del Galdo F, Haines III GK, Jaffe ML, Jimenez SA, Seibold JR, Koch AE. The proadhesive phenotype of systemic sclerosis skin promotes myeloid cell adhesion. Abstract, ACR National Meeting, 2008.
2007 ACR Annual Meeting
- Schiopu E, Impens AJ, Phillips K, Denton CP, Furst DE, Guillevin L, Rugin LJ, Wells AU, Matucci-Cerinic M, Riemekasten G, Emery P, Chadha-Boreham H, Charef P, Roux S Black CM, Seibold JR. Sub-maximal exercise testing in the prospective assessment of interstitial lung disease (ILD) secondary to systemic sclerosis (SSc): Correlations with objective and subjective measures of parenchymal lung disease. Abstract, ACR National Meeting, 2007.
- Schiopu E, Hsu VM, Hummers L, Shapiro L, Mayes MD, Csuka ME, Derk C, Chung L, Varga J, Furst DE, Silver RM, Wigley FM, Seibold JR, Steen VD. Pulmonary hypertension assessment and reaction of outcomes in scleroderma (systemic sclerosis, SSc): PHAROS. Abstract, ACR National Meeting, 2007.
- Impens AJ, Schiopu E, Phillips K, Denton CP, Furst DE, Guillevin L, Rubin LJ, Wells AU, Matucci-Cerinic M, Riemekasten G, Emory P, Chada-Boreham H, Charef P, Roux S, Black CM, Seibold JR. Correlations of objective ratings of respiratory function with traditional measures of parenchymal lung disease in systemic sclerosis (SSc) patients with interstitial lung disease. Abstract, ACR National Meeting, 2007.
- Impens AJ, Schiopu E, Buch MH, Seibold JR. Physician and patient assessment of disease severity in systemic sclerosis (SSc). Abstract, ACR National Meeting, 2007.
- Impens AJ, Guerriere J, Schiopu E, Gendrano N, Seibold JR, Rosen RC. Sexual activity and functioning in female scleroderma (SSc) patients. Abstract, American Psychological Association National Meeting, 2007.
- Impens AJ, Chung KC, Buch MH, Schiopu E, Kotsis S, Burns P, Seibod JR. Comparison of pain scales in systemic sclerosis (SSc) patients. Abstract, EULAR, 2007.
2006 ACR Annual Meeting
- Impens AJ, Chung KC, Buch MH, Schiopu E, Kotsis S, Burns P, Seibold JR. Influences of clinical features of systemic sclerosis (SSc) on the Michigan Hand Questionnaire (MHQ). Abstract, ACR National Meeting, 2006.
- Impens AJ, Chung KC, Buch MH, Schiopu E, Kotsis S, Burns P, Seibold JR. Validation of the Michigan Hand Outcomes Questionnaire (MHQ) in Systemic Sclerosis (SSc). Abstract, ACR National Meeting, 2006.
- Schiopu E, Hsu VM, Impens AJ, Guerriere-Rothman JA, McCloskey DA, Wilson JE, Seibold JR. Controlled trial of Tadalafil in Raynaud Phenomenon (RP) secondary to systemic sclerosis (SSc). Abstract, ACR National Meeting, 2006. Â
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