Pfingst Laboratory Publications

  • Zhou N, Pfingst BE Evaluating multipulse integration as a neural-health correlate in human cochlear implant users: Relationship to spatial selectivity. J Acoust Soc Am, 140 (3), 1537-1547, 2016. DOI: 10.1121/1.4962230. View Article
  • Schvartz-Leyzac KC, Pfingst BE Across-site patterns of electrically evoked compound action potential amplitude-growth functions in multichannel cochlear implant recipients and the effects of the interphase gap. Hear Res, 341, 50-65, 2016.
    DOI: 10.1016/j.heares.2016.08.002. View Article
  • Zhou N, Pfingst BE Evaluating multipulse integration as a neural-health correlate in human cochlear-implant users: Relationship to forward-masking recovery. JASA Express Letters, 139 (3), EL71-75, Published Online: 15 MAR 2016.
    DOI: 10.1121/1.4943783. PMID: 27036290; PMC Journal - In Process. View Article
  • Pfingst BE, Hughes AP, Colesa DJ, Watts MM, Strahl SB, Raphael Y Insertion trauma and recovery of function after cochlear implantation: Evidence from objective functional measures. Hear Res, 330, 98-105, 2015. DOI: 10.1016/j.heares.2015.07/010. PMID 4674315; PMC Journal - In Process; Available on 1 DEC 2016. View Article
  • Zhou N, Kraft CT, Colesa DJ, Pfingst BE Integration of pulse trains in humans and guinea pigs with cochlear implants. J Assoc Res Otolaryngol, 16, 523-534, 2015.
    DOI: 10.1007/s10162-015-0521-0. PMCID: PMC4488162. View Article
  • Budenz CL, Wong HT, Swiderski DL, Shibata SB, Pfingst BE, Raphael Y Differential effects of AAV.BDNF and AAV.Ntf3 in the deafened adult guinea pig ear. Sci Rep, 5, 8619, 2015.
    DOI: 10.1038/srep08619. PMC Journal in Process. View Article
  • Pfingst BE, Zhou N, Colesa DJ, Watts MM, Strahl SB, Garadat SN, Schvartz-Leyzac KC, Budenz CL, Raphael Y, Zwolan TA Importance of cochlear health for implant function. Hear Res, 322, 77-88, 2015. DOI 10.1016/j.heares.2014.09.009. PMCID: PMC4377117. View Article 
  • Zhou N, Pfingst, BE.  Relationship between multipulse integration and speech recognition with cochlear implants. J Acoust Soc Am 136:1257-1268, 2014. View Article
  • Zhou N, Pfingst BE.  Effects of site-specific level adjustments on speech recognition with cochlear implants. Ear Hear 35:30-34, 2014.  DOI:  10.1097/AUD.0b013e31829d15cc. PMCID: PMC3872508. View Article
  • Garadat SN, Zwolan TA, Pfingst BE.  Using temporal modulation sensitivity to select stimulation sites for processor maps in cochlear implant listeners. Audiol Neurotol 18:247-260, 2013.  DOI:  10.1159/000351302. PMCID: PMC3874548. View Article
     
  • Budenz CL, Pfingst BE, Raphael Y. The use of neurotrophin therapy in the inner ear to augment cochlear implantation outcomes. Anat Rec, 295, 1896-1908. DOI: 10.1002/ar.22586. PMCID: PMC4081524. View Article 
  • Zhou N and Pfingst BE. Psychophysically based site selection coupled with dichotic stimulation improves speech recognition in noise with bilateral cochlear implants. J Acoust Soc Am 132:994-1008, 2012. View Article 
  • Garadat S.N., Zwolan T.A., and Pfingst B.E. Across-site patterns of modulation detection: Relation to speech recognition. J Acoust Soc Am 131:4030-4041, 2012. Erratum: J Acoust Soc Am 134:715, 2013. DOI: 10.1121/1.4807575. View Article
  • Zhou N., Xu L., and Pfingst B.E. Characteristics of detection thresholds and maximum comfortable loudness levels as a function of pulse rate in human cochlear implant users. Hear Res 284: 25-32, 2012. DOI: 10.1016/j.heares.2011.12.008. NIHMSID: 355951. View Article
  • Chikar J.A., Hendricks J.L., Crumling M.A., Richardson-Burns S.M., Raphael, Y., Pfingst B.E., Martin D.C. The use of dual PEDOT an dRGD-functionalized alginate hydrogel coating to provide sustained drug delivery and improved cochlear implants function. Biomaterials. 33:1982-1990, 2012. DOI:10.1016/j.biomaterials.2011.11.1052. PMCID: PMC3261353. View Article
  • Pfingst, B.E., Colesa, D.J., Hembrador, S., Kang, S.Y., Middlebrooks, J.C., Raphael, Y., Su, G.L. Detection of pulse trains in the electrically stimulated cochlea: Effects of cochlear health. J Acoust Soc Am 130:3954-3968, 2011. View Article
  • Pfingst, B.E., Bowling, S.A., Colesa, D.J., Garadat, S.N., Raphael, Y., Shibata, S.B., Strahl, S.B., Su, G.L., Zhou, N. Cochlear infrastructure for electrical hearing. Hear Res 281:65-73, 2011. View Article
  • Shibata, S.B., Budenz, C.L., Bowling, S.A., Pfingst, B.E., Raphael, Y. Nerve maintenance and regeneration in the damaged cochlea. Hear Res 281:56-64, 2011. View Article
  • Pfingst, B.E. Effects of electrode configuration on cochlear implant modulation detection thresholds. J Acoust Soc Am129:3908-3915, 2011. View Article
  • Garadat, S.N., Pfingst, B.E. Relationship between gap detection thresholds and loudness in cochlear-implant users. Hear Res 275:130-138, 2011. View Article
  • Shibata, S.B., Cortez, S.R., Beyer, L.A., Wiler, J.A., Di Polo, A., Pfingst, B.E., Raphael, Y. Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleae. Exp Neurol 223:464-472, 2010. View Article
  • Kang, S.Y., Colesa, D.J., Swiderski, D.L., Su, G.L., Raphael, Y., Pfingst, B.E.. Effects of hearing preservation on psychophysical responses to cochlear implant stimulation. J Assoc Res Otolaryngol 11:245-265, 2010. View Article
  • Chikar JA, Batts SA, Pfingst BE, Raphael Y. Visualization of spiral ganglion neurites within the scala tympani with a cochlear implant in situ. J Neurosci Meth 179:201-207, 2009. View Article
  • Chikar JA, Colesa DJ, Swiderski DL, Di Polo, A, Raphael Y, Pfingst BE Over-expression of BDNF by adenovirus with concurrent electrical stimulation improves cochlear implant thresholds and survival of auditory neurons. Hear Res 245:24-34, 2008. View Article
  • Su GL, Colesa DJ, Pfingst BE. Effects of deafening and cochlear implantation procedures on postimplantation psychophysical electrical detection thresholds. Hear Res 241:64-72, 2008. View Article
  • Pfingst BE, Burkholder-Juhasz RA, Xu, L, Thompson CS. Across-site patterns of modulation detection in listeners with cochlear implants. J Acoust Soc Am 123:1054-1062, 2008. View Article
  • Xu L, Pfingst BE. Spectral and temporal cues for speech recognition: Implications for auditory prostheses. Hear Res. 242: 132-140, 2008. View Article
  • Pfingst BE, Xu L, Thompson CS. Effects of carrier pulse rate and stimulation site on modulation detection by subjects with cochlear implants. J Acoust Soc Am 121:2236-2246, 2007. View Article
  • Drennan WR, Pfingst BE. Current-level discrimination in the context of interleaved multichannel stimulation in cochlear implants: Effects of number of stimulated electrodes, pulse rate and electrode separation. J Assoc Res Otolaryngol 7:308-316, 2006. View Article
  • Xu L, Zwolan TA, Thompson CS, Pfingst BE. Efficacy of a cochlear-implant simultaneous analog stimulation strategy coupled with a monopolar electrode configuration. Ann Otol Rhinol Laryngol 114:886-893, 2005.
  • Pfingst BE, Xu L. Psychophysical metrics and speech recognition in cochlear implant users. Audiol Neurotol 10:331-341, 2005. View Article
  • Xu L, Thompson CS, Pfingst BE. Relative contributions of spectral and temporal cues for phoneme recognition. J Acoust Soc Am 117:3255-3267, 2005. View Article
  • Drennan WR, Pfingst BE. Current-level discrimination using bipolar and monopolar electrode configurations in cochlear implants. Hear Res 202:170-179, 2005. View Article
  • Pfingst BE, Xu L, Thompson CS. Across-site threshold variation in cochlear implants: Relation to speech recognition. Audiol Neurotol 9:341-352, 2004. View Article
  • Pfingst BE, Xu L. Across-site variation in detection thresholds and maximum comfortable loudness levels for cochlear implants. J Assoc Res Otolaryngol 5:11-24, 2004. View Article
  • Franck KH, Xu L, Pfingst BE. Effects of stimulus level on speech perception with cochlear prostheses. J Assoc Res Otolaryngol 4:49-59, 2003. View Article
  • Xu L, Pfingst BE. Relative importance of temporal envelope and fine structure in lexical-tone perception. J Acoust Soc Am 114:3024-3027, 2003. View Article
  • Xu L, Tsai Y, Pfingst BE. Features of stimulation affecting tonal-speech perception: Implications for cochlear prostheses. J Acoust Soc Am 112:247- 258, 2002. View Article
  • Pfingst BE, Franck KH, Xu L, Bauer EM, Zwolan TA. Effects of electrode configuration and place of stimulation on speech perception with cochlear prostheses, J Assoc Res Otolaryngol 2: 87-103, 2001. View Article
  • Miller, A.L.,Arenberg, J.G., Middlebrooks,J.C., Pfingst, B.E. Cochlear implant thresholds: Comparison of middle latency responses with psychophysical and cortical-spike-activity thresholds. Hear Res 152: 55-66, 2001. View Article
  • Pfingst BE: Auditory Prostheses. In J K Chapin and KA Moxon (eds.), Neural Prostheses for Restoration of Sensory and Motor Function, CRC Press, Inc., Boca Raton, Florida, pp. 3-43, 2000.
  • Miller AL, Morris DJ, Pfingst BE. Effects of time after deafening and implantation on guinea pig electrical detection thresholds. Hear Res 144: 175-186, 2000. View Article
  • Morris DJ, Pfingst BE. Effects of electrode configuration and stimulus level on rate and level discrimination with cochlear implants, J Assoc Res Otolaryngol 1: 211-223, 2000. View Article
  • Pfingst BE, Holloway LA, Zwolan TA, Collins LM. Effects of stimulus level on electrode-place discrimination in human subjects with cochlear implants. Hear Res 134:105-115, 1999. View Article
  • Miller AL, Smith DW, Pfingst BE. Across-species comparisons of psychophysical detction thresholds for electrical stimulation of the cochlea: II. Strength-duration functions for single biphasic pulses. Hear Res 135: 47-55, 1999. View Article
  • Miller AL, Smith DW, Pfingst BE. Across-species comparisons of psychophysical detection thresholds for electrical stimulation of the cochlea: I. Sinusoidal stimuli. Hear Res 134:89-104, 1999. View Article
  • Saito H, Miller JM, Pfingst BE, Altschuler RA. Fos-like immunoreactivity in the auditory brain stem evoked by bipolar intracochlear electrical stimulation: Effects of current level and pulse duration. Neurosci 91:139-161, 1999. View Article
  • Pfingst BE, Montney LM, Bledsoe SC. Comparison of psychophysical and neural thresholds in response to electrical stimulation of the cochlea in guinea pigs. Proceedings of the 16th International Congress on Acoustics and the 135th Meeting of the Acoustical Socety of America, pp. 871-872, 1998.
  • Pfingst BE, Zwolan TA, Holloway LA. Effects of stimulus configuration on psychophysical operating levels and on speech recognition with cochlear implants. Hear Res 112:247-260, 1997.
  • Miller AL, Morris DJ, Pfingst BE. Interactions between pulse separation and pulse polarity order in cochlear implants. Hear Res 109:21-33, 1997. View Article
  • Pfingst BE, Holloway LA, Razzaque SA. Effects of pulse separation on detection thresholds for electrical stimulation of the human cochlea. Hear Res 98:77-92, 1996.
  • Coste RL, Pfingst BE. Stimulus features affecting psychophysical detection thresholds for electrical stimulation of the cochlea. III: Pulse polarity. J Acoust Soc Am 99:3099-3108. 1996.
  • Miller CA, Faulkner MJ, Pfingst BE. Functional responses from guinea pigs with cochlear implants. II. Changes in electrophysiological and psychophysical measures over time. Hear Res 92:100-111, 1995.
  • Miller CA, Woodruff KE, Pfingst BE. Functional responses from guinea pigs with cochlear implants. I. Electrophysiological and psychophysical measures. Hear Res 92:85-99, 1995.
  • Pfingst BE, Morris DJ, Miller AL. Effects of electrode configuration on threshold functions for electrical stimulation of the cochlea. Hear Res 85:76-84, 1995.
  • Spelman FA, Pfingst BE, Clopton BM, Jolly CN, Rodenhiser KL. The effects of electrical current configuration on potential fields in the electrically-stimulated cochlea: Field models and measurements. Ann Otol Rhinol Laryngol (St. Louis) 104 - Supplement 166:131-136, 1995.
  • Pfingst BE, Miller AL, Morris DJ, Zwolan TA, Spelman FA, Clopton BM. Effects of electrical-current configuration on stimulus detection. Ann Otol Rhinol Laryngol (St. Louis) 104 - Supplement 166:127-131, 1995.
  • Pfingst BE, Holloway LH, Poopat N, Subramanya AR, Warren MF, Zwolan TA: Effects of stimulus level on nonspectral frequency discrimination by human subjects. Hear Res 78:197-209, 1994.
  • Pfingst BE, Morris DJ: Stimulus features affecting psychophysical detection thresholds for electrical stimulation of the cochlea. II: Frequency and interpulse interval. J Acoust Soc Am 94:1287-1294, 1993.
  • Niparko JK, Pfingst BE, Johansson C, Kileny PR, Kemink JL, Tjellström A: Cochlear-wall titanium implants for auditory nerve stimulation. Ann Otol Rhinol Laryngol (St Louis), 102:447-454, 1993.
  • Moon AK, Zwolan TA, Pfingst BE: Effects of phase duration on detection of electrical stimulation of the human cochlea. Hear Res 67:166-178, 1993.
  • Pfingst BE: Comparison of spectral and nonspectral frequency difference limens for human and nonhuman primates. J Acoust Soc Am 93:2124-2129, 1993.
  • Barretto RL, Pfingst BE: Electrical stimulation of the auditory nerve: effects of pulse width on frequency discrimination. Hear Res 62:245-249, 1992.
  • Pfingst BE, DeHaan DR and Holloway LA: Stimulus features affecting psychophysical detection thresholds for electrical stimulation of the cochlea. I: Phase duration and stimulus duration. J Acoust Soc Am 90:1857-1866, 1991.
  • Glass I, Spelman FA and Pfingst BE: Discrimination of complex electrical stimulation through a multichannel intracochlear implant. J Basic Clin Physiol Pharmacol 2:87-102, 1991.
  • Pfingst BE: Changes over time in thresholds for electrical stimulation of the cochlea. Hear Res 50:225-236, 1990.
  • Pfingst BE and Rai DT: Effects of level on nonspectral frequency difference limens for electrical and acoustic stimuli. Hear Res 50:43-56, 1990.
  • Pfingst BE: Psychophysical constraints on biophysical/neural models of threshold. In: JM Miller and FA Spelman (eds.), Cochlear Implants. Models of the Electrically Stimulated Cochlea, Springer-Verlag, New York, pp. 161-185, 1989.
  • Pfingst BE, Albrektsson T, Tjellström A, Miller JM, Zappia J, Xue X and Weiser F: Chronic skull-anchored percutaneous implants in nonhuman primates. J Neurosci Meth 29:207-216, 1989.
  • Xue X and Pfingst BE: Inner ear implants for experimental electrical stimulation of auditory nerve arrays. J Neurosci Meth 28:189-196, 1989. View Article
  • Pfingst BE, Miller JM, Tjellström A, Albrektsson T and Carlisle L: Development of cochlear-wall implants for electrical stimulation of the auditory nerve. Acta Otolaryngol 107:210-218, 1989.
  • Pfingst BE: Stimulus parameters affecting the discrimination of temporal frequency cues. In: P Banfai (ed.), Cochlear Implant: Current Situation, Bermann, Erkelenz, West Germany: pp. 51-65, 1988.
  • Pfingst BE: Comparisons of psychophysical and neurophysiological studies of cochlear implants. Hear Res 34:243-252, 1988.
  • Pfingst BE and Rush NL: Discrimination of simultaneous frequency and level changes in electrical stimuli. Ann Otol Rhinol Laryngol (St. Louis) 96: Supplement 128, 34-37, 1987.
  • Miller JM, Pfingst BE, Tjellström A, Albrektsson T, Thompson P and Kemink JL: Titanium implants in the otic capsule: Development of a new multichannel extracochlear implant. Am J Otology 8:230-233, 1987.
  • Pfingst BE, Glass I, Spelman FA and Sutton D: Psychophysical studies of cochlear implants in monkeys: Clinical implications. In: RA Schindler and MM Merzenich (eds.), Cochlear Implants, Raven Press, New York, pp. 305-322, 1985.
  • Miller JM, Duckert L, Sutton D, Pfingst BE and Malone M: Animal models: Relevance to implant use in humans. In: RA Schindler and MM Merzenich (eds.), Cochlear Implants, Raven Press, New York, pp. 35-54, 1985.
  • Pfingst BE and Sutton D: Relation of psychophysical thresholds for electrical stimuli to auditory nerve survival: Summary of results from 18 scala tympani implants. Abstracts of the Seventh Midwinter Research Meeting, Association for Research in Otolaryngology 10, 1984.
  • Pfingst BE: Operating ranges and intensity psychophysics for cochlear implants. Implications for speech processing strategies. Arch Otolaryngol 110:140-144, 1984. View Article
  • Miller JM, Duckert LG, Malone MA and Pfingst BE: Cochlear prostheses: Stimulation-induced damage. Ann Otol Rhinol Laryngol (St. Louis) 92:599-609, 1983. View Article
  • Pfingst BE, Burnett PA and Sutton D: Intensity discrimination with cochlear implants. J Acoust Soc Am 73:1283-1292, 1983. View Article
  • Pfingst BE and Sutton D: Relation of cochlear implant function to histopathology in monkeys. Ann NY Acad Sci 405:224-239, 1983.
  • Clopton BM, Spelman FA, Glass I, Pfingst BE, Miller JM, Lawrence PD and Dean DP: Neural encoding of electrical signals. Ann NY Acad Sci 405:146-158, 1983.
  • Spelman FA, Clopton BM and Pfingst BE: Tissue impedance and current flow in the implanted ear: Implications for the cochlear prosthesis. Ann Otol Rhinol Laryngol (St. Louis) 91: Supplement 98, 3-8, 1982.
  • Pfingst BE, Sutton D, Miller JM and Bohne BA: Relation of psychophysical data to histopathology in monkeys with cochlear implants. Acta Otolaryngol 92:1-13, 1981.
  • Sutton D, Miller JM and Pfingst BE: Comparison of cochlear histopathology following two implant designs for use in scala tympani. Ann Otol Rhinol Laryngol (St. Louis) 89: Supplement 66, 11-14, 1980.
  • Spelman FA, Clopton BM, Pfingst BE and Miller JM: Design of the cochlear prosthesis: Effects of the flow of current in the implanted ear. Ann Otol Rhinol Laryngol (St. Louis) 89: Supplement 66, 8-10, 1980.
  • Pfingst BE, Spelman FA and Sutton D: Operating ranges for cochlear implants. Ann Otol Rhinol Laryngol (St. Louis) 89: Supplement 66, 1-4, 1980.
  • Spelman FA, Pfingst BE, Miller JM, Hassul M, Powers WE and Clopton BM: Biophysical measurements in the implanted cochlea. Otolaryngol Head Neck Surg 88:183-187, 1980.
  • Spelman FA, Pfingst BE, Powers WE, Miller JM, Hassul M and Clopton BM: Biophysics of the implanted ear: Electrical parameters. In: DL McPherson (ed.), Advances in Prosthetic and Technical Devices for the Deaf: A Technical Workshop, National Technical Institute for the Deaf, Rochester, NY, pp. 312-323, 1979.
  • Pfingst BE: Psychophysical studies of cochlear prosthesis in animals. In: DL McPherson (ed.), Advances in Prosthetic and Technical Devices for the Deaf: A Technical Workshop, National Technical Institute for the Deaf, Rochester, NY, pp. 275-280, 1979.
  • Pfingst BE, Donaldson JA, Miller JM and Spelman FA: Psychophysical evaluation of cochlear prostheses in a monkey model. Ann Otol Rhinol Laryngol (St. Louis) 88:613-625, 1979.