Dr. Vazquez’s research focuses on neural, vascular and metabolic imaging of normal brain function in vivo with extensions to neurological pathologies, especially Alzheimer’s disease. He uses an array of computational and optical methodologies, such as linear/non-linear modeling and characterization of biological systems, optical/fluorescence imaging, two-photon microscopy, calcium imaging, optogenetics and magnetic resonance imaging, to assess nervous system function and dysfunction. Although these methods are mostly implemented in animal models, he focuses on methods that can be adapted or applied to humans (e.g. PET or fMRI). It is the goal to blend imaging modalities in order to advance our understanding of brain function and develop new avenues for the quantification of physiological and functional parameters that can be used to study, diagnose and/or treat brain pathologies. We have placed emphasis on cell-type specific contributions to neuro-vascular and neuro-metabolic mechanisms in healthy subjects, neuro-vascular and neurons-metabolic dysfunction in models of brain injury and neuro-degenerative disease (Alzheimer's), and the development of new imaging markers and biomarkers of neurodegeneration (in collaboration with PET-Radiology, ADRD and Dept. of Neurology).
Functional MRI Speaker Series - Alberto L. Vazquez, Ph.D.
Herbert H. Dow Building, Room 1014 or
via Zoom: https://umich.zoom.us/j/96772739218, passcode: 864498
Speaker: Alberto L. Vazquez, Ph.D.
Associate Professor, Departments of Radiology and Bioengineering, University of Pittsburgh
Presentation Title: Dissection of Brain Network Activity and Neuronal Cell-Type Specificity Using High-Resolution fMRI