Tuesday, April 2, 2024

Advanced MRI and MRS Imaging Technologies to Study Brain Function and Neuroenergetics under Healthy and Diseased State at Ultrahigh Field

12:00 PM to 1:00 PM

2200 Bonnisteel Blvd.
Ann Arbor, MI 48109
LBME, Room 1170 

Functional MRI Laboratory—CoE Seminar featuring Dr. Wei Chen, a Professor in the Departments of Radiology and Biomedical Engineering at the University of Minnesota.

Abstract:      
Magnetic resonance and spectroscopic imaging (MRI and MRSI) technology is unique and powerful to noninvasively image and study brain structure, function and networks, cerebral metabolism and neuroenergetics, neurophysiology, and pathology. Newly developed ultrahigh field MRI and MRSI technology significantly improves imaging sensitivity, resolution, and reliability. In this talk, I will briefly introduce the state-of-the-art magnetic resonance imaging technologies developed in my lab and their applications for healthy and diseased brains. Finally, I will discuss a new technology development of a multimodal neuroimaging approach enabling simultaneous two-photon microscopic imaging and functional MRI in the mouse brain at 16.4 Tesla, thus, bridging the neuroimaging scale from macroscopic, mesoscopic to the microscopic level.

Dr. Wei Chen

Professor, Department of Radiology
Professor, Department of Biomedical Engineering
University of Minnesota

Dr. Wei Chen is a professor in the Departments of Radiology and Biomedical Engineering at the University of Minnesota. After receiving a science bachelor’s degree in physical chemistry from Fudan University in 1981, he became a teacher at the same university. In 1985, he studied at the Department of Chemistry at Washington University in St. Louis and received his Ph.D. in 1990. For three years, he was a postdoctoral and researcher fellow at Yale University School of Medicine. In 1994, he joined the world-renowned Center for Magnetic Resonance Research (CMRR) at the University of Minnesota and became a tenured full professor in 2002. His research focuses on developing ultrahigh field magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) technologies to study brain cellular energy metabolism, neuroenergetics, brain function, and dysfunction. He has received many National Institutes of Health (NIH) research grants, including three Brain Initiative grants. He is a reviewer for reviewing NIH grant proposals and manuscripts of scientific journals and is a member of the editorial board of imaging journals. He has published a large number of influential papers. He is a fellow for the International Society of Magnetic Resonance in Medicine (ISMRM) and the American Institute of Biomedical Engineering (AIMBE).