Adam Lauring, MD, PhD
Professor of Internal Medicine
Professor of Microbiology and Immunology
Professor of Ecology and Evolutionary Biology
[email protected]

Available to mentor

Adam Lauring, MD, PhD
Professor
  • About
  • Links
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Dr. Lauring is a physician-scientist with a research interest in the genetics and evolution of RNA viruses

    Links
    • Lauring Lab
    Qualifications
    • MD
      University of Washington, Seattle, 2002
    • PhD
      University of Washington, Seattle, 2000
    • BS
      Yale University, New Haven, 1994
    Research Overview

    Dr. Lauring’s laboratory has worked in three main areas. First, they study the importance of mutation rate and mutational tolerance to the evolution of poliovirus and influenza virus. More recently, they have utilized next generation sequencing of patient samples to define the within-host evolution and transmission of influenza virus, poliovirus, and SARS-CoV-2. Since the beginning of the COVID pandemic, his laboratory has collaborated with large teams to study the genomic epidemiology of respiratory viruses and the effectiveness of vaccines against them.

    Recent Publications See All Publications
    • Journal Article
      SARS-CoV-2 shedding and evolution in patients who were immunocompromised during the omicron period: a multicentre, prospective analysis.
      Raglow Z, Surie D, Chappell JD, Zhu Y, Martin ET, Kwon JH, Frosch AE, Mohamed A, Gilbert J, Bendall EE, Bahr A, Halasa N, Talbot HK, Grijalva CG, Baughman A, Womack KN, Johnson C, Swan SA, Koumans E, McMorrow ML, Harcourt JL, Atherton LJ, Burroughs A, Thornburg NJ, Self WH, Lauring AS, Investigating Respiratory Viruses in the Acutely Ill (IVY) Network . Lancet Microbe, 2024 Mar; 5 (3): e235 - e246. DOI:10.1016/S2666-5247(23)00336-1
      PMID: 38286131
    • Journal Article
      Interim Effectiveness of Updated 2023-2024 (Monovalent XBB.1.5) COVID-19 Vaccines Against COVID-19-Associated Emergency Department and Urgent Care Encounters and Hospitalization Among Immunocompetent Adults Aged ≥18 Years - VISION and IVY Networks, September 2023-January 2024.
      DeCuir J, Payne AB, Self WH, Rowley EAK, Dascomb K, DeSilva MB, Irving SA, Grannis SJ, Ong TC, Klein NP, Weber ZA, Reese SE, Ball SW, Barron MA, Naleway AL, Dixon BE, Essien I, Bride D, Natarajan K, Fireman B, Shah AB, Okwuazi E, Wiegand R, Zhu Y, Lauring AS, Martin ET, Gaglani M, Peltan ID, Brown SM, Ginde AA, Mohr NM, Gibbs KW, Hager DN, Prekker M, Mohamed A, Srinivasan V, Steingrub JS, Khan A, Busse LW, Duggal A, Wilson JG, Chang SY, Mallow C, Kwon JH, Exline MC, Columbus C, Vaughn IA, Safdar B, Mosier JM, Harris ES, Casey JD, Chappell JD, Grijalva CG, Swan SA, Johnson C, Lewis NM, Ellington S, Adams K, Tenforde MW, Paden CR, Dawood FS, Fleming-Dutra KE, Surie D, Link-Gelles R, CDC COVID-19 Vaccine Effectiveness Collaborators . MMWR Morb Mortal Wkly Rep, 2024 Feb 29; 73 (8): 180 - 188. DOI:10.15585/mmwr.mm7308a5
      PMID: 38421945
    • Journal Article
      Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness - United States.
      Frutos AM, Price AM, Harker E, Reeves EL, Ahmad HM, Murugan V, Martin ET, House S, Saade EA, Zimmerman RK, Gaglani M, Wernli KJ, Walter EB, Michaels MG, Staat MA, Weinberg GA, Selvarangan R, Boom JA, Klein EJ, Halasa NB, Ginde AA, Gibbs KW, Zhu Y, Self WH, Tartof SY, Klein NP, Dascomb K, DeSilva MB, Weber ZA, Yang D-H, Ball SW, Surie D, DeCuir J, Dawood FS, Moline HL, Toepfer AP, Clopper BR, Link-Gelles R, Payne AB, Chung JR, Flannery B, Lewis NM, Olson SM, Adams K, Tenforde MW, Garg S, Grohskopf LA, Reed C, Ellington S, CDC Influenza Vaccine Effectiveness Collaborators . MMWR Morb Mortal Wkly Rep, 2024 Feb 29; 73 (8): 168 - 174. DOI:10.15585/mmwr.mm7308a3
      PMID: 38421935
    • Journal Article
      Effectiveness of Bivalent mRNA COVID-19 Vaccines in Preventing SARS-CoV-2 Infection in Children and Adolescents Aged 5 to 17 Years.
      Feldstein LR, Britton A, Grant L, Wiegand R, Ruffin J, Babu TM, Briggs Hagen M, Burgess JL, Caban-Martinez AJ, Chu HY, Ellingson KD, Englund JA, Hegmann KT, Jeddy Z, Lauring AS, Lutrick K, Martin ET, Mathenge C, Meece J, Midgley CM, Monto AS, Newes-Adeyi G, Odame-Bamfo L, Olsho LEW, Phillips AL, Rai RP, Saydah S, Smith N, Steinhardt L, Tyner H, Vandermeer M, Vaughan M, Yoon SK, Gaglani M, Naleway AL. JAMA, 2024 Feb 6; 331 (5): 408 - 416. DOI:10.1001/jama.2023.27022
      PMID: 38319331
    • Preprint
      Durability of protection from original monovalent and bivalent COVID-19 vaccines against COVID-19-associated hospitalization and severe in-hospital outcomes among adults in the United States — September 2022–August 2023
      DeCuir J, Surie D, Zhu Y, Lauring AS, Gaglani M, McNeal T, Ghamande S, Peltan ID, Brown SM, Ginde AA, Steinwand A, Mohr NM, Gibbs KW, Hager DN, Ali H, Frosch A, Gong MN, Mohamed A, Johnson NJ, Srinivasan V, Steingrub JS, Khan A, Busse LW, Duggal A, Wilson JG, Qadir N, Chang SY, Mallow C, Kwon JH, Exline MC, Shapiro NI, Columbus C, Vaughn IA, Ramesh M, Safdar B, Mosier JM, Casey JD, Talbot HK, Rice TW, Halasa N, Chappell JD, Grijalva CG, Baughman A, Womack KN, Rhoads JP, Swan SA, Johnson C, Lewis N, Ellington S, McMorrow M, Self WH, Network IRVITAI. medRxiv, DOI:10.1101/2024.01.07.24300910
    • Journal Article
      Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike.
      Wang Q, Guo Y, Liu L, Schwanz LT, Li Z, Nair MS, Ho J, Zhang RM, Iketani S, Yu J, Huang Y, Qu Y, Valdez R, Lauring AS, Huang Y, Gordon A, Wang HH, Liu L, Ho DD. Nature, 2023 Dec; 624 (7992): 639 - 644. DOI:10.1038/s41586-023-06750-w
      PMID: 37871613
    • Journal Article
      Vaccine Effectiveness Against Influenza A-Associated Hospitalization, Organ Failure, and Death: United States, 2022-2023.
      Lewis NM, Zhu Y, Peltan ID, Gaglani M, McNeal T, Ghamande S, Steingrub JS, Shapiro NI, Duggal A, Bender WS, Taghizadeh L, Brown SM, Hager DN, Gong MN, Mohamed A, Exline MC, Khan A, Wilson JG, Qadir N, Chang SY, Ginde AA, Mohr NM, Mallow C, Lauring AS, Johnson NJ, Gibbs KW, Kwon JH, Columbus C, Gottlieb RL, Raver C, Vaughn IA, Ramesh M, Johnson C, Lamerato L, Safdar B, Casey JD, Rice TW, Halasa N, Chappell JD, Grijalva CG, Talbot HK, Baughman A, Womack KN, Swan SA, Harker E, Price A, DeCuir J, Surie D, Ellington S, Self WH, Investigating Respiratory Viruses in the Acutely Ill (IVY) Network . Clin Infect Dis, 2023 Dec 5; DOI:10.1093/cid/ciad677
      PMID: 38051664
    • Journal Article
      Rapid transmission and tight bottlenecks constrain the evolution of highly transmissible SARS-CoV-2 variants.
      Bendall EE, Callear AP, Getz A, Goforth K, Edwards D, Monto AS, Martin ET, Lauring AS. Nat Commun, 2023 Jan 17; 14 (1): 272 DOI:10.1038/s41467-023-36001-5
      PMID: 36650162