1150 W. Medical Center Drive
Ann Arbor, MI 48109
Available to mentor
Alice Telesnitsky earned her BS degree in Genetics at the University of California, Davis in 1979. She earned her PhD in Biochemistry from the University of California, Berkley in 1988. She performed her post-doctorate fellowship at the College of Physicians and Surgeons Laboratory of Dr. Stephen Goff, Columbia University in New York. She joined the faculty at the University of Michigan, Ann Arbor in 1994, and currently resides over a lab studying the functions and dynamics of RNA in the context of retroviral replication, mechanisms of retroviral genetic variation, and the epigenetics of HIV-1 persistence.
Telesnitsky Lab
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Postdoctoral FellowCollege of Physicians and Surgeons, New York, 1994
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PhDUniversity of California, Berkeley, Berkeley, 1988
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BSUniversity of California, Davis, Davis, 1979
* Retroviral genomic RNA structure, dynamics, and molecular recognition
* Epigenetics of HIV persistence
* Mechanisms of retroviral genetic variation
* Reverse transcriptase enzymology and the process of reverse transcription
* Determinants and roles of host RNAs in retroviral particles
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Kharytonchyk S, Burnett C, Gc K, Telesnitsky A. J Virol, 2023 Sep 28; 97 (9): e0081823Journal ArticleTranscription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements.
DOI:10.1128/jvi.00818-23 PMID: 37681957 -
Kharytonchyk S, Burnett C, Gc K, Telesnitsky A. 2023 May 22;PreprintTranscription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements.
DOI:10.1101/2023.05.22.541776 PMID: 37292892 -
Telesnitsky A, Atindaana E, Gopal K, Emery S, Kidd J, Telesnitsky A. Journal of Virus Eradication, 2022 Dec; 8: 100185Journal ArticlePP 3.5 – 00110 The proviral quasispecies of HIV-1
DOI:10.1016/j.jve.2022.100185 -
Atindaana E, Kissi-Twum A, Emery S, Burnett C, Pitcher J, Visser M, Kidd JM, Telesnitsky A. mBio, 2022 Apr 26; 13 (2): e0374821Journal ArticleBimodal Expression Patterns, and Not Viral Burst Sizes, Predict the Effects of Vpr on HIV-1 Proviral Populations in Jurkat Cells.
DOI:10.1128/mbio.03748-21 PMID: 35384697 -
Blakemore RJ, Burnett C, Swanson C, Kharytonchyk S, Telesnitsky A, Munro JB. Biophys J, 2021 Nov 2; 120 (21): 4874 - 4890.Journal ArticleStability and conformation of the dimeric HIV-1 genomic RNA 5'UTR.
DOI:10.1016/j.bpj.2021.09.017 PMID: 34529947 -
Atindaana E, Emery S, Burnett C, Pitcher J, Kidd J, Telesnitsky A. 2021 bioRxiv,PreprintVpr shapes the proviral landscape and polyclonal HIV-1 reactivation patterns in cultured cells
DOI:10.1101/2021.10.08.463623 -
Ding P, Kharytonchyk S, Kuo N, Cannistraci E, Flores H, Chaudhary R, Sarkar M, Dong X, Telesnitsky A, Summers MF. Proc Natl Acad Sci U S A, 2021 Sep 14; 118 (37):Journal Article5'-Cap sequestration is an essential determinant of HIV-1 genome packaging.
DOI:10.1073/pnas.2112475118 PMID: 34493679 -
Esquiaqui JM, Kharytonchyk S, Drucker D, Telesnitsky A. RNA, 2021 Jun 1; 6: 708 - 714.Journal ArticleHIV Spliced RNAs display transcription start site bias
