Jaime Fuentes

Microbiology & Immunology
Ph.D. Student
Lab PI - Eric Martens

Bacteriophage (phages) were some of the earliest genetic models and with recent developments in the field of human gut microbiome research, has transformed our understanding of the microbiology that exists within each of us. Within the competitive human gut environment numerous challenges exist for commensal bacterial species including predation by numerous phage families, which are among the most prevalent biological entities within the gut and a play role in modulating host immune responses. My research focus is at the interface of these two disciplines to discover how common human gut bacteria have evolved to persist despite constant pressure by phage. Specifically, my work is focused on the role of phase variable surface protein expression as a mechanism for phage evasion in the human gut symbiont Bacteroides thetaiotaomicron.