Frank Brosius, MD

Frank C. Brosius, III, MD

Professor Emeritus, Internal Medicine-Nephrology
Professor Emeritus, Molecular and Integrative Physiology
Division of Nephrology
1560 MSRB II
Ann Arbor MI 48109-5676
Diabetic Kidney Disease

Using systems biology and translational approaches to identify biomarkers and create treatments for diabetic complications

Dr. Brosius' research focuses on identification of new targets for the treatment of diabetic kidney disease, the major cause of kidney failure in the world. One such target identified by him and his colleagues was the JAK/STAT signaling pathway. A recent clinical trial, co-led by Dr. Brosius, showed that a JAK inhibitor led to positive results in patients with diabetic kidney disease. He currently is a principal investigator on a National Institutes of Health R24 grant to identify additional targets for intervention in kidney, nerve and eye complications of diabetes. He has served on multiple committees and working groups related to his clinical and research interests with the Veterans Affairs Hospital, American Society of Nephrology, National Kidney Foundation, American Heart Association and American Diabetes Association.


  • MD, University of Kansas, 1979
  • Residency, University of Michigan Hospital, Internal Medicine, 1980-83
  • Fellowship, Beth Israel Hospital, Nephrology Division, Clinical and Research Fellow, 1985-1989
  • Fellowship, Whitehead Institute for Biomedical Research, Research Fellow, 1986-1989

Honors & Awards

  • University of Michigan, Chairs' Award for Outstanding Service, 2016
  • Florida Hospital, Orlando, Distinguished Lectureship, 2013
  • American Heart Association, KCVD Distinguished Achievement Award,  2011
  • University of Michigan, Taubman Institute Senior Scholar, 2014