Dr. Callaghan won this grant from the National Institutes of Health (R01DK115687) to evaluate approaches for preventing diabetic neuropathy. The study will test two approaches. First, participants will be divided into two groups, one that undergoes bariatric surgery (weight-loss surgery) and one that does not. Second, participants from each group (surgery and no surgery) will be divided randomly into high intensity exercise or regular exercise. Patients will be evaluated for neuropathy to determine the most effective approach(es). This study is registered at ClinicalTrials.gov (NCT03617185).