Areas of Interest
The Burgess lab focuses on the neural circuitry underlying learning and behavior.
Specifically, projects focus on how motivation-, arousal-, and feeding-related circuits can modulate higher-order brain areas and their responses to learned cues in the environment.
Current studies are attempting to understand how specific hunger- and sleep-promoting circuits in the hypothalamus can facilitate learning of, and appropriate responses to, motivationally relevant sensory cues.
A combination of techniques and approaches is used to map neural circuits in mice, including neuroanatomy, behavior, optogenetics, and in vivo calcium imaging. The goal is to identify specific neuronal projections, record their activity during motivated behaviors and learning, and manipulate their activity to demonstrate a functional role in behavior.
Honors & Awards
NARSAD Brain and Behavior Research Foundation Young Investigator Grant - January 2019
Michigan Diabetes Research Center Pilot and Feasibility Grant - December 2018
Whitehall Foundation New Investigator Award - September 2018
Michigan Biological Sciences Scholar Program Award - January 2018
Published Articles or Reviews
Intermingled Ensembles in Visual Association Cortex Encode Stimulus Identity or Predicted Outcome.
Ramesh RN, Burgess CR, Sugden AU, Gyetvan M, Andermann ML. Neuron. 2018 Nov 21;100(4):900-915.e9. doi: 10.1016/j.neuron.2018.09.024. Epub 2018 Oct 11.
Gating of visual processing by physiological need.
Burgess CR, Livneh Y, Ramesh RN, Andermann ML. Curr Opin Neurobiol. 2018 Apr;49:16-23. doi: 10.1016/j.conb.2017.10.020. Epub 2017 Nov 8. Review.
Homeostatic circuits selectively gate food cue responses in insular cortex.
Livneh Y, Ramesh RN, Burgess CR, Levandowski KM, Madara JC, Fenselau H, Goldey GJ, Diaz VE, Jikomes N, Resch JM, Lowell BB, Andermann ML. Nature. 2017 Jun 29;546(7660):611-616. doi: 10.1038/nature22375. Epub 2017 Jun 14.
To view a complete list, visit https://www.ncbi.nlm.nih.gov/pubmed/?term=Burgess+Christian%5BAuthor%5D