Joanna Mattis, M.D., Ph.D.

Michigan Neuroscience Institute Affiliate
Assistant Professor of Neurology

BSRB 5023




Joanna Mattis, MD, PhD, is a physician scientist with a clinical and research specialization in epilepsy. Dr. Mattis earned a combined BS, MS degree in Neurobiology at Yale University and an MPhil in Physiology, Development, and Neuroscience at the University of Cambridge. She then completed an MD, PhD at Stanford University, obtaining her PhD in the laboratory of Dr. Karl Deisseroth, credited as co-founder of the field of optogenetics. She moved to the University of Pennsylvania to complete a Neurology residency and Epilepsy fellowship. After completion of her clinical training, she was appointed as Instructor in Neurology, gaining further expertise in experimental epileptology. Dr. Mattis joined the faculty at the University of Michigan as an Assistant Professor of Neurology in June 2022. The Mattis laboratory will focus on the characterization and manipulation of neuronal circuits in preclinical epilepsy models.

Published Articles or Reviews

Corticohippocampal circuit dysfunction in a mouse model of Dravet syndrome
Mattis J, Somarowthu A, Goff KM, Jiang E, Yom J, Sotuyo NP, McGarry LM, Feng H, Kaneko K, Goldberg EM. eLife 11:e69293, February 2022 [PDF] [DOI] [PubMed]

Reciprocal Lateral Hypothalamic and Raphe GABAergic Projections Promote Wakefulness
Gazea M, Furdan S, Sere P, Oesch L, Molnár B, Di Giovanni G, Fenno LE, Ramakrishnan C, Mattis J, Deisseroth K, Dymecki SM, Adamantidis AR, LÅ‘rincz ML. J Neurosci. 41(22):4840-4849, June 2021 [PDF] [DOI] [PubMed]

A Guide to Creating and Testing New INTRSECT Constructs
Fenno LE, Mattis J, Ramakrishnan C, Deisseroth K. Current Protocols in Neuroscience 80(4):4.39.1-4.39.24, July 2017 [PDF] [DOI] [PubMed]

Clinical Reasoning: A young woman with progressive headache and pancytopenia
Conrad EC, Siegler JE, Mattis J, Schnure N, Messé SR. Neurology 88(14):e132-e136, April 2017 [PDF] [DOI] [PubMed]


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