Areas of Interest
The remarkable information processing capacity of neurons in the mammalian brain stems from the intricate organization of their synaptic connections and the ability of these synapses to change with experience. In brain areas such as the hippocampus, the ability of principal neurons to accommodate dense networks of synaptic connectivity is critical for higher cognitive functions such as learning and memory.
The Sutton lab is interested in the molecular mechanisms that control the development, maintenance and plasticity of these synapses, and in particular, how the compartmentalization of these processes in dendrites can service the unique demands of different synaptic sites impinging on the same neuron. A combination of electrophysiology, biochemistry, and molecular approaches in conjunction with high-resolution imaging in living neurons is employed to study these questions.
Null strain analysis of submerged aneurysm analogues using a novel 3D stereomicroscopy device.
Lane BA, Lessner SM, Vyavahare NR, Sutton MA, Eberth JF. Comput Methods Biomech Biomed Engin. 2020 Feb 18:1-13. doi: 10.1080/10255842.2020.1724974. [Epub ahead of print]
A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis.
Rodriguez CM, Wright SE, Kearse MG, Haenfler JM, Flores BN, Liu Y, Ifrim MF, Glineburg MR, Krans A, Jafar-Nejad P, Sutton MA, Bassell GJ, Parent JM, Rigo F, Barmada SJ, Todd PK. Nat Neurosci. 2020 Mar;23(3):386-397. doi: 10.1038/s41593-020-0590-1. Epub 2020 Feb 17.
Accelerometer activity tracking in horses and the effect of pasture management on time budget.
Maisonpierre IN, Sutton MA, Harris P, Menzies-Gow N, Weller R, Pfau T. Equine Vet J. 2019 Nov;51(6):840-845. doi: 10.1111/evj.13130. Epub 2019 Jun 17.
Radiation Tolerance of Nanopore Sequencing Technology for Life Detection on Mars and Europa.
Sutton MA, Burton AS, Zaikova E, Sutton RE, Brinckerhoff WB, Bevilacqua JG, Weng MM, Mumma MJ, Johnson SS. Sci Rep. 2019 Mar 29;9(1):5370. doi: 10.1038/s41598-019-41488-4.
For a complete list, visit https://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&db=PubMed&term=sutton+ma