Parag Patil, MD, PhD photo

Parag G. Patil, M.D., Ph.D.

Michigan Neuroscience Institute Affiliate
Associate Professor, Neurosurgery, Neurology, Anesthesiology, and Biomedical Engineering
Associate Chair, Clinical and Translational Research
Faculty, Neuroscience Graduate Program

UMH Neurosurgery
3470 TC SPC 5338


Parag G. Patil, M.D., Ph.D., joined the faculty at the University of Michigan in 2005. A native of Pennsylvania, he attended MIT, where he received a B.S. in electrical engineering. After graduation, he was awarded a Marshall Scholarship to study Philosophy and Economics at Magdalen College, Oxford University in the UK. On returning to the U.S., Dr. Patil pursued combined medical and doctoral studies in biomedical engineering at Johns Hopkins University, followed by a neurosurgery residency at Duke University and a fellowship at the University of Toronto.

Dr. Patil is currently an Associate Professor of Neurosurgery, Neurology, Anesthesiology, and Biomedical Engineering. He additionally serves as Associate Chair for Clinical and Translational Research and in leadership roles in diverse multi-disciplinary, multi-investigator research efforts and national societies. His academic goal is to utilize engineering and mathematical techniques, along with interdisciplinary collaboration, to improve neuroprosthetics and perform translational neuroscience research. His NIH and NSF-funded research focuses on electrophysiology, imaging, mathematical modeling, and the development of improved therapies for the treatment of paralysis, pain, and movement disorders using neural-interface devices. Dr. Patil has mentored over 50 students and postdocs, fostering the development of translational clinicians, engineers, and scientists.

Areas of Interest

  • Developing brain-machine interfaces for neuroprosthetic applications
  • Intraoperative studies of human sensation
  • Modeling and neuroimaging to individualize intraoperative DBS targeting
  • Defining structure-function relationships underlying clinical outcomes in STN DBS for Parkinson's disease
  • Stem-Cell Therapies for Neurological Restoration

Published Articles or Reviews

  • Nason SR, Mender MJ, Vaskov AK, Willsey MS, Ganesh Kumar N, Kung TA, Patil PG, Chestek CA. Real-time linear prediction of simultaneous and independent movements of two finger groups using an intracortical brain-machine interface. Neuron. 2021 Oct 6;109(19):3164-3177.e8. doi: 10.1016/j.neuron.2021.08.009. Epub 2021 Sep 8. PubMed PMID: 34499856; PubMed Central PMCID: PMC8549035.
  •  Willsey MS, Lu CW, Nason SR, Malaga KA, Lempka SF, Chestek CA, Patil PG. Distinct perceptive pathways selected with tonic and bursting patterns of thalamic stimulation. Brain Stimul. 2020 Sep - Oct;13(5):1436-1445. doi: 10.1016/j.brs.2020.07.007. Epub 2020 Jul 23. PubMed PMID: 32712343.
  •  Lu CW, Harper DE, Askari A, Willsey MS, Vu PP, Schrepf AD, Harte SE, Patil PG. Stimulation of zona incerta selectively modulates pain in humans. Sci Rep. 2021 Apr 26;11(1):8924. doi: 10.1038/s41598-021-87873-w. PubMed PMID: 33903611; PubMed Central PMCID: PMC8076305.
  • Malaga KA, Costello JT, Chou KL, Patil PG. Atlas-independent, N-of-1 tissue activation modeling to map optimal regions of subthalamic deep brain stimulation for Parkinson disease. Neuroimage Clin. 2021;29:102518. doi: 10.1016/j.nicl.2020.102518. Epub 2020 Dec 3. PubMed PMID: 33333464; PubMed Central PMCID: PMC7736726.

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