Biography
Dr. Hanson completed her postdoctoral work at Yale in membrane trafficking before joining the Department of Cell Biology and Physiology at Washington University in 1997. She joined the University of Michigan in 2018 as the Minor J. Coon Professor and Departmental Chair.
Dr. Hanson is an associate editor of the Journal of Biological Chemistry and a member of the American Society of Cell Biology, the American Society for Biochemistry and Molecular Biology, and the American Association for the Advancement of Science. She served as chair of the NIH Synapses, Cytoskeleton and Trafficking Study Section and recently served as chair of the National Institutes of Health (NIH) Membrane Biology and Protein Processing Study Section.
Areas of Interest
Dr. Hanson’s research focuses on understanding how proteins interact to regulate the structure and organization of cell membranes both inside and outside the cell and has implications for understanding a wide range of diseases, including, among others, neurodegenerative disorders such as Alzheimer’s disease and the debilitating movement disorder, dystonia. Specific areas of interest include protein-protein and protein-membrane interactions involved in membrane trafficking and organelle structure, focusing on ESCRTs, AAA+ ATPases, and associated machinery.
Honors & Awards
- Elected Fellow, American Association for the Advancement of Science (2016)
- Gerty T. Cori Professorship, Washington University School of Medicine (2016)
- Distinguished Young Scholar in Medical Research, W.M. Keck Foundation, (1999)
- Searle Scholar Award (1999)
Credentials
- B.A., Molecular Biophysics and Biochemistry, Yale University
- M..D., Ph.D., Stanford University School of Medicine
Published Articles or Reviews
- A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.(link is external) Zhang W, Yang X, Chen L, Liu YY, Venkatarangan V, Reist L, Hanson P, Xu H, Wang Y, Li M. PLoS Biol. 2021; 19: e3001361.
- ESCRT puts its thumb on the nanoscale: Fixing tiny holes in endolysosomes. Bohannon KP, Hanson PI. Curr Opin Cell Biol. 2020; 65: 122–30.
- A cell-based assay for CD63-containing extracellular vesicles. Cashikar AG, Hanson PI. PLoS One. 2019; 14: e0220007.
- Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response. Mittal E, Skowyra ML, Uwase G, Tinaztepe E, Mehra A, Köster S, Hanson PI, Philips JA. mBio. 2018; 9: e01765-18.
- For a list of publications from PubMed, click HERE