Samantha Regan, Ph.D.

MNI Postdoctoral Community Leader
Research Fellow, Human Genetics
Bielas Lab

Areas of Interest

My area of interest is aimed at understanding the genetic and molecular mechanisms of neurodevelopmental disorders. 

Honors & Awards

  • Developmental Neurotoxicology Society Early Investigator Award
  • University of Cincinnati Dean’s Dissertation Completion Fellowship
  • Society for Neuroscience Trainee Professional Development Award
  • American Society for Human Genetics Reviewer’s Choice Abstract


  • Ph.D., Neuroscience, University of Cincinnati
  • B.A., Biology and Neuroscience, Oberlin College

Published Articles or Reviews

  • Regan SL, Cryan MT, Williams MT, Vorhees CV, Ross AE. Rapid Detection of Striatal Transient Dopamine Release in Lphn3 KO rats using Fast Scan Cyclic Voltammetry. ACS Chem. Neuroscience. 2020 Apr 15;11(8):1171-1177. doi: 10.1021/acschemneuro.0c00033.
  • Regan SL, Hufgard JR, Pitzer EM, Sugimoto C, Yueh-Chiang Hu, Williams MT, Vorhees CV. Knockout of brain-specific Latrophilin-3 (Lphn3) in rats disrupts striatal dopamine resulting in hyperactivity, hyper-reactivity, and under-response to dopamine activation by amphetamine. Neurobiology of Disease. 2019 130:104494. doi: 10.1016/j.nbd.2019.104494.
  • Regan SL, Pitzer EPM, Hufgard JL, Sugimoto C, Williams MT, Vorhees C. A novel role for the ADHD risk gene latrophilin-3 in learning and memory in Lphn3 knockout rats. Neurobiol Dis. 2021;158:105456. doi: 10.1016/j.nbd.2021.105456.
  • Regan SL, Sugimoto C, Williams MT, Vorhees CV. Heterozygous Lphn3 KO rats recapitulate hyperactivity and cognitive deficits. Genes Brain Behav. 2022 21::e12817. doi: 10.1111/gbb.12817.