Samuel Kwon, Ph.D.

Michigan Neuroscience Institute Affiliate
Assistant Professor of Molecular, Cellular, and Developmental Biology

Biological Sciences Building (BSB)
Room 4264
1105 N University Ave, Ann Arbor, MI 48109



Samuel Kwon, Ph.D., received his B.Sc. in 2004 from The Australian National University and a Ph.D. in Physiology in 2011 at the University of Wisconsin-Madison. Dr. Kwon's served as a postdoctoral fellow at Johns Hopkins University Medical School and joined the University of Michigan in January 2018 as an Assistant Professor of Behavioral and Systems Neuroscience (Sensory Neuroscience).

Areas of Interest

The Kwon lab focuses on cellular, molecular and circuit mechanisms underlying the plasticity in mammalian brain using in vivo imaging, electrophysiology, opto/pharmacogenetics, and behavior.

Kwon’s scientific training spans the breadth of the neurosciences, with training in molecular, cellular, synaptic and behavioral studies in mice. Kwon is currently focused on using tools to monitor and quantify neuronal plasticity at cellular and circuit levels in the intact mouse sensory cortex during sensory experience and perceptual learning. By combining this approach with mouse genetic tools, Kwon aims to understand specific cell types and circuits that are causally involved in plasticity and learning, and how alterations in these mechanisms lead to neurocognitive disorders.

Published Articles or Reviews

  • Chang C, Zhao M, Grudzien S, Oginsky MF, Yang Y and Kwon SE. (2022) A cortico-cortical pathway targets inhibitory interneurons and modulates paw movement during locomotion in mice, Journal of Neuroscience 42(1): 44-57.
  • Kwon SE. (2018) Interplay between cortical state and perceptual learning: a focused review, Frontiers in Systems Neuroscience 09 Oct: fnsys.2018.00047.
  • Kwon SE, Yang H, Minamisawa G and O’Connor DH. (2016) Propagation of sensory and decision- related activity in a cortical feedback loop during touch perception, Nature Neuroscience 19(9): 1243-9.
  • *Yang H, *Kwon SE, Severson KS and O’Connor DH. (2016) Origins of choice-related activity in mouse somatosensory cortex, Nature Neuroscience 19(1): 127-34.

Web Sites