Molecular phenotyping studies constitute a critical element in providing new insights into metabolic derangements that underlie obesity, its complications and nutritional disorders. The broad array of services provided by the MPC will assure that a larger cohort of investigators can take advantage of the technology. In addition to providing instrumental infrastructure, the Core staff will provide consultation and collaboration to apply molecular phenotyping studies in nutrition and obesity research.
Identification and quantification of metabolites are provided in association with the Michigan Regional Comprehensive Metabolomics Resource Center (MRC2) and the Biomedical Research Core Facilities (BRCF Metabolomics core). Epigenomic studies will be facilitated through the BRCF Epigenomics Core.
Our services include:
- Consultation and training in molecular phenotyping analyses including metabolomics, in vitro metabolic assessment including mitochondrial metabolism via Sea Horse Analyzer, epigenetics and optogenetics.
- Access to senior personnel highly skilled in molecular phenotyping techniques.
- Access to state-of-the-art instrumentation and services for molecular phenotyping analysis.
- Develop and/or implement new technologies beneficial to MNORC investigators.