Areas of Interest
My laboratory has worked on intermediate filament proteins since 1989, and our work focuses on understanding the disease association, function and regulation of keratins and lamins in digestive organs. A related relevant area of focus is drug screening to identify potential compound that may have therapeutic benefit for the more than 70 intermediate filament associated diseases for which directed therapies are completely lacking. Two other major areas we are involved with are aimed at defining biomarkers for acute and chronic liver and pancreatic diseases, and pursuing molecular understanding of porphyria pathogenesis and related therapeutic approaches.
- Ph.D., University of California, San Diego, 1980
- M.D., University of Miami, 1984