Mentors & Projects for Research Track Students

This list offers examples of research projects that may be available to RESEARCH TRACK students. 

This list is subject to change.  Please email MSPhysiology@umich.edu to request the most updated Mentors list.

Systems Engineering Approaches to Understanding the Biophysical and Biochemical Operation of Physiological Systems

Faculty: Daniel Beard

Desired Experience:

  • A background in physical sciences (chemistry, physics) engineering or applied mathematics would be useful

Thyroid Cell Growth, Death, and the Cell Biology of Thyroglobulin Protein Transport in Thyrocytes

Faculty: Peter Arvan

Desired Experience:

  • Prior work in a research laboratory is desirable. Ability to work with mice and mouse tissues is desirable.

Map Neural Circuits, Manipulate Neuronal Projections, and Manipulate Their Activity to Demonstrate a Functional Role in Behavior

Faculty: Christian Burgess

Desired Experience:

  • None specified.

Evaluating the Impact of Diabetes on the Expression of Retinal Crystallins in Humans

Faculty: Patrice Fort

Desired Experience:

  • None specified.

Translational Research Focused on Defining the Molecular Causes of Human Adrenal Diseases

Faculty: William Rainey

Desired Experience:

  • Interested applicants must have at least some research experience.

Effect of Sestrins on Exercise and Mobile Capacity OR Identification of New Autophagy Mediators in Drosophila System OR Molecular Mechanisms Underlying Hepatoprotective Function of Sestrins in Mouse Liver

Faculty: Jun Hee Lee

Desired Experience

  • Basic molecular biology and genetics background.

Investigate the Role of mTOR Signaling in Normal and Diabetic Tissues and Cells

Faculty: Thomas Gardner

Desired Experience

  • None specified.

Identify Novel Genes Involved With Increasing Resistance to Toxic Stress, and Their Role in Health and Longevity

Faculty: Scott Leiser

Desired Experience

  • Some Basic molecular biology experience and basic knowledge of genetics.

Anterograde Identification of Monosynaptic Neuronal Afferents to POMC Neurons

Faculty: Malcolm Low

Desired Experience 

  • Previous experience handling mice and a solid background in both neurobiology and molecular biology. 

Metabolic Networks in the Tumor Microenvironment

Faculty: Costas Lyssiotis

Desired Experience

  • None specified.

Discovery of Atrial Fibrillation in Stroke Inpatients

Faculty: Jimo Borjigin

Desired Experience

  • Each student will be trained following joining the laboratory. Dedication, responsibility, and attention to detail are traits required for this project.

Disruption of Mechanosignalling in Muscle Cells, Nitric Oxide, and Blood Flow - Extreme Muscle Fatigue Therapies; OR Plasma Membrane Repair in Muscle Cells Related to Muscular Dystrophy

Faculty: Daniel Michele

Desired Experience

  • Previous wet bench experience in a basic research laboratory as an undergraduate student is helpful.

Identifying Pathological Circuit Changes in Brains From Animals Exposed to Noise 

Faculty: Susan Shore

Desired Experience

  • Lab experience is desirable, but not essential. 

Utilizing Mathematical, Computational, and Statistical Methods to Select Experiments Investigating Protein Aggregation and Fibrillation

Faculty: Santiago Schnell

Desired Experience

  • Students familiar with calculus, dynamical systems theory, and computer programming will be preferred.

Role of oxygen signaling in intestinal cancer

Faculty: Yatrik Shah

Desired Experience

  • Will train.
  • Willing to work with animals.

Role of Adipocyte Genes in Adipogenesis and Metabolism

Faculty: Ormond MacDougald

Desired Experience

  • Lab experience and the desire to create new information.

Cellular and Molecular Mechanisms of Post-Traumatic Osteoarthritis

Faculty: Tristan Maerz

Desired Experience

  • None specified.

Identify Methods For Restoring The Function of Auditory Circuits For Individuals with Hearing Disorders of Hearing Loss

Faculty: Michael Roberts

Desired Experience

  • None specified.

Identify Amino Acids Residues in NOTCH3 That Result in Pathological Protein Transformation OR Characterize Behavioral, Brain Structural, and Physiological Changes In Mice That Produce Altered NOTCH3 Protein

Faculty: Michael Wang

Desired Experience

  • A strong desire to learn and flexibility of thinking are major requirements.

Exploring Neocortical Structure-Function; OR Cortical Networks During Sleep And Wake Cycles; OR Antidepressant Action in Mammalian Systems

Faculty: Brendan Watson

Desired Experience

  • None specified.

The Molecular Regulation of Beige Fat Function; OR The Therapeutic Potential of Human Beige Fat; OR The Developmental Origin of Beige Fat Precursors

Faculty: Jun Wu  

Desired Experience

  • Some prior lab experience is preferred.

Examine The Cross-Regulation Between E4BP4 and PPARalpha Pathway During Hepatic ER Stress

Faculty: Lei Yin

Desired Experience

  • Experience working in a lab during college is desirable.

Generate and Validate Novel Alpaca-Derived Nanobodies; OR Improve CRISPRa Technology for C. elegans; OR Use C. elegans To Screen For Genes That Regulate Chaperone Activity In the Presence Of Aggregation-Prone Proteins.

Faculty: Mattias C. Truttmann

Desired Experience

  • Basic training in molecular biology, biochemistry, or genetics is a plus.

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This list is updated regularly.