Jimo Borjigin

Jimo Borjigin, PhD

Associate Professor, Molecular & Integrative Physiology
Associate Professor, Neurology

7732C, Medical Science II
1137 E. Catherine St.
Ann Arbor, MI 48109-5622

(734) 763-5453

Areas of Interest

The main research interests of the Borjigin lab include:

  • Mechanisms of sudden cardiac arrest and the role of the brain during cardiac arrest (brain-heart coupling).
  • Neural basis of covert consciousness in normal and abnormal brain states in human subjects.
  • Mechanisms of endogenous DMT synthesis.
  • Visualizing covert brain (and heart) activities in patients with neurological, psychological, and psychiatric disorders, to assist with their clinical prognosis, diagnosis, and treatment.

Honors & Awards

  • The John Merck Scholars Award - 1999
  • Michigan Biological Sciences Scholar Program Award - 2003


  • Ph.D., Johns Hopkins, 1994

Published Articles or Reviews

  • Xu, G., Mihaylova, T., Li, D., Tian, F., Farrehi, P.M., Parent, J.M., Mashour, G.A., Wang, M.M., Borjigin*, J. Surge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain (2023). Proc. Natl. Acad. Sci. USA, 2023 May 9;120(19):e2216268120. doi: 10.1073/pnas.2216268120. Epub 2023 May 1. PMID: 37126719.
  • Glynos, N.G., Carter, L., Lee, S.J., Kim, Y., Kennedy, R.T., Mashour, G.A., Wang, M.M., Borjigin*, J. Indolethylamine N-methyltransferase (INMT) is not essential for endogenous tryptamine-dependent methylation activity in rats (2023). Scientific Reports. 13(1):280. doi: 10.1038/s41598-023-27538-y. PMID: 36609666; PMCID: PMC9822953.
  • Brown, D., Xu, G., Belinky, A., Buhay, N., Blaha, M., Wang, M.M., Farrehi, P., and Borjigin*, J. Electrocardiomatrix facilitates accurate detection of atrial fibrillation in stroke patients (2019), Stroke. 2019 Jul;50(7):1676-1681.
  • Dean, J., Liu, T., Huff, S., Sheler, B., Barker, S.A., Strassman, R.J., Wang, M.M., and Borjigin*, J. Biosynthesis and extracellular concentration of N, N-dimethyltryptamine in Mammalian Brain (2019), Scientific Reports. 2019 Jun 27;9(1):9333.
  • Li D, Mabrouk OS, Liu T, Tian F, Xu G, Rengifo S, Choi SJ, Mathur A, Crooks CP, Kennedy RT, Wang MM, Ghanbari H, Borjigin* J. Asphyxia-activated corticocardiac signaling accelerates onset of cardiac arrest. Proc Natl Acad Sci U S A. 2015 Apr 6. pii: 201423936.
  • Borjigin*, J., Lee, U., Liu, T., Pal, D., Huff, S., Klarr, D., Sloboda, J., Hernandez, J., Wang, M.M., Mashour, G.A. Surge of neurophysiological coherence and connectivity in the dying brain (2013). Proc. Natl. Acad. Sci. USA, 110(35):14432-7.

Complete List of Publications.

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