Dr. Lei Yin received her Ph.D. degree from the Department of Molecular and Cellular Biology at the University of Connecticut, Storrs in May 2003. After her postdoc studies at the University of Pennsylvania in Philadelphia from 2003-2009, Dr. Lei Yin joined the faculty of MIP in the fall of 2009.
Areas of Interest
My research interest is in investigating the signaling pathways that promote or remove ubiquitination of a protein target and the biological consequences on circadian clock and metabolism. We also study how altered clock protein ubiquitination pathways contribute to onset, progression and therapy of fatty liver diseases. In the lab, we use a combination of genetic (both knockout out and transgenic mice), molecular (gene expression, promoter reporter assay and epigenetic modifications) and biochemical approaches (protein-protein interaction, in vitro and in vivo ubiquitnation assay, protein half-life assay) to address our specific hypothesis.
Honors & Awards
2009 Biological Scholar program, University of Michigan
2007 NIH Pathway to Independence Award K99/R00
Ph.D. from Depart of Molecular and Cellular Biology at the University of Connecticut, Storrs