Louis D'Alecy

Louis G. D'Alecy, DMD, PhD

Professor Emeritus, Molecular & Integrative Physiology

7620A Med Sci II
1137 Catherine St.
Ann Arbor, MI 48109-5622

Biography

I am a classical Professor of Physiology and love to work at the bench at mechanistically challenging in vivo and in vitro experimentation.  As Sequence Director for the Cardiovascular and Respiratory Sequences for 1ST year Medical Students I spend a lot of time in the classroom.  I direct the telemetry core facility making available continuous conscious monitoring of blood pressure and ECG in mice and rats.  I try to be the best grandpa to five grandchildren. 

Areas of Interest

Preventive and therapeutic interventions are pursued as well as basic mechanisms of cell damage. Whole animal studies using either anesthetized or conscious preparations are complemented by in vitro preparations, where appropriate, to test physiologically important hypotheses. Systemic hypoxia, regional ischemia and cardiac arrest/resuscitation models, in mice, rats and dogs are used sequentially and simultaneously to acquire data relevant to the resolution of clinical problems. Undergraduate, graduate, medical, and postdoctoral participation is encouraged at all levels of laboratory activity.  Current projects involve HPLC analysis of endogenous NOS inhibitors involved in endothelial dysfunction.  Accumulation of NOS inhibitors in stored blood used for transfusion suggests one mechanism for adverse responses to blood transfusion and possible therapeutic compensations.  

Honors & Awards

  • 2000-Medical Student award For Teaching Excellence Winter
  • 2001-Teacher of the Month , from The University of Michigan
  • 2001-Kaiser Permanente Award for Excellence in Preclinical Teaching
  • 2003-TAMS Award (Token of Appreciation from Medical Students (Class 0f 2003)
  • 2004-Distinguished Faculty Governance Award 
  • 2010-Endowment for the Basic Sciences (EBS) Teaching Award in Physiology
  • 2013-League of Educational Excellence

Credentials

  • D.M.D., Ph.D. University of Pennsylvania, 1971

Published Articles via PubMed