Friday, March 12, 2021

Neurology/Neuroscience Research Seminar

12:00 PM to 1:00 PM

CME credit available, click here

Virtual event

 Zoom ID: 910 4550 7427 Passcode: 776945

Stress is the key precipitant for depression and other psychiatric disorders. Uncovering the mechanisms linking stress and disease holds the potential to inform interventions to successfully block the pathologic effects of stress. However, because stress is typically unpredictable, it has been difficult to follow the effects of stress prospectively in humans. Physician training is a rare situation where a substantial increase in stress can be reliably predicted. Through the Intern Health Study, a prospective cohort study following over 22,500 training physicians, we have found a 6-fold increase in depression with the start of internship training. In this talk, I will discuss findings from the Intern Health Study on 1) predictors of depression during medical training 2) interactions between genomic predisposition and stress of depression and 3) mobile technology as a tool to track objective markers of stress.

“Physician Training: A Prospective Model to Understand how Stress Leads to Depression”

Srijan Sen, M.D., Ph.D.

Frances and Kenneth Eisenberg Professor of Depression and Neurosciences
Director, Frances and Kenneth Eisenberg and Family Depression Center
Associate Vice President for Research - Health Sciences
Research Professor, Michigan Neuroscience Institute