Friday, May 28, 2021

Neurology/Neuroscience Research Seminar

12:00 PM to 1:00 PM

CME credit available, click here

Virtual event

Meeting ID: 910 4550 7427 Passcode: 829259

The seminar will provide an overview of the challenges in defining pathogenic mechanisms in a heterogeneous disease like amyotrophic lateral sclerosis (ALS), and how the use of patient derived samples helps identify genes and pathways that can then be further investigated in cell based or animal models of disease. Both unbiased and targeted proteomic methodologies have been used to discover biomarkers from human biofluids and pathways altered during ALS. Novel animal models have been generated to explore function consequences of disease causing MATR3 mutations, and initial efforts using precision medicine to treat ALS will be presented.

"Use of ALS Patient-Derived Samples to Identify Biomarkers, Mechanisms of Disease, and Precision Medicine Approaches of Treatment"

Robert Bowser, Ph.D.

Deputy Chief Scientific Officer, Professor and Chair, Department of Neurobiology Barrow Neurological Institute & St. Joseph’s Hospital and Medical Center