Research Assistant Professor
Neurology
[email protected]
Available to mentor
Lisa M Sharkey
Research Assistant Professor
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Sharkey L. 2023 Dec 5;PresentationFrom Mutations to Mechanisms: UBQLN2's Role in Protein Quality Control and Neurodegenerative Disease
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Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL. Sci Rep, 2023 Jan 6; 13 (1): 293Journal ArticleUbiquilin-2 regulates pathological alpha-synuclein.
DOI:10.1038/s41598-022-26899-0 PMID: 36609661 -
Desai AA, Zupancic JM, Trzeciakiewicz H, Gerson JE, DuBois KN, Skinner ME, Sharkey LM, McArthur N, Ferris SP, Bhatt NN, Makowski EK, Smith MD, Chen H, Huang J, Jerez C, Kane RS, Kanaan NM, Paulson HL, Tessier PM. bioRxiv, 2023 Jul 4;Journal ArticleFlow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils.
DOI:10.1101/2023.07.04.547698 PMID: 37461643 -
Idera A, Sharkey LM, Kurauchi Y, Kadoyama K, Paulson HL, Katsuki H, Seki T. J Pharmacol Sci, 2023 Jul; 152 (3): 182 - 192.Journal ArticleWild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways.
DOI:10.1016/j.jphs.2023.05.002 PMID: 37257946 -
Sharkey L. 2023 May 3;PresentationUbiquilin2’s role in neuronal protein quality control pathways
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Sharkey L. 2023 May 12;PresentationUncovering critical roles for retrotransposon-derived proteins in Ubiquilin-2 (UBQLN2) biology; implications for ALS research
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Sharkey L. 2023 Apr 7;PresentationUncovering critical roles for retrotransposon-derived proteins in Ubiquilin-2 (UBQLN2) biology; implications for ALS research
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Benyair R, Giridharan SSP, Rivero-Ríos P, Hasegawa J, Bristow E, Eskelinen E-L, Shmueli MD, Fishbain-Yoskovitz V, Merbl Y, Sharkey LM, Paulson HL, Hanson PI, Patnaik S, Al-Ramahi I, Botas J, Marugan J, Weisman LS. Autophagy Rep, 2023 2 (1):Journal ArticleUpregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
DOI:10.1080/27694127.2023.2166722 PMID: 37064812