“The full FDA approval of lecanemab is a remarkable milestone in the treatment of Alzheimer’s disease. We now have a disease-modifying therapy approved based on its clinical benefit,” said Dr. Judy Heidebrink.
Natural light signals our brains to be up-and-at-’em, says Dr. Deirdre Conroy. So open the window and soak in the first light to activate your energy. Dehydration seriously compounds fatigue, so be sure to drink a glass of water too.
“One of the challenges with melatonin is that recent studies have shown that the dose on the bottle may not always equate to exactly how much is in each pill,” Dr. Conroy says. "A lower dose of melatonin has been shown to show a bigger 'shift' in the circadian phase than larger doses of melatonin."
Some studies suggest that women are 40 per cent more likely to experience sleep disruption than men. And throughout a woman’s life, puberty, pregnancy, menopause and caring responsibilities may all have an effect on the amount of good quality sleep available to women.
It has to do with the severity of the memory issues. Concerns arise when memory issues are “significant, daily and involve large episodes,” explains Henry Paulson, M.D., Ph.D. “If I can’t remember that I had dinner three nights ago with six people, that’s a concern.”
"It is likely appropriate that some with mild cognitive impairment are still driving, but for some it may not be," said Dr. Lewis B. Morgenstern. "Close family may have discussions with aging loved ones about Advance Driving Directives, These are agreements between an aging person and a loved one about having conversations about driving cessation."
"This is really the first breakthrough in terms of a disease-modifying therapy. One that directly targets one of the key pathologies of Alzheimer's disease that's been approved based on a clinical benefit, so it's a really exciting breakthrough in the field," said Judith Heidebrink, a neurologist at Michigan Medicine who worked on phase II
Mark Reimers and his co-investigator Christian Burgess at the University of Michigan were able to develop a prototype of the imaging system that has the potential to image 10,000 to 20,000 neurons, giving researchers an unprecedented view of brain activity in real time while it is making and recalling memories.
Concerns arise when memory issues are “significant, daily and involve large episodes,” explains Henry Paulson, M.D., Ph.D., “If I can’t remember that I had dinner three nights ago with six people, that’s a concern.”
“Our study found that Mexican American people who spoke only Spanish had worse neurologic outcomes three months after having a stroke than Mexican American people who spoke only English or were bilingual,” said study author Lewis B. Morgenstern, M.D.
“We’d love to halt the progression or reverse the progression (of the disease), but this is the first kind of foot in the door to these more beneficial therapies to really change the course of someone’s disease. For someone with early symptoms, if we can slow it down, that’s six months more independence in a certain task," said Dr. Heidebrink.