Associate Professor of Neurology
Ann Arbor
MI
48109,
[email protected]
MI
48109,
Available to mentor
Stephen A Goutman, MD, MS
Associate Professor
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FellowshipCleveland Clinic, Neuromuscular Medicine, 2012
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ResidencyCleveland Clinic, Neurology, 2011
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MSUniversity of Michigan, Rackham School of Graduate Studies, Ann Arbor, 2015
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MDUniversity of Chicago Pritzker School of Medicine, 924 East 57th Street Suite 104, 2007
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BAJohns Hopkins University, Baltimore, 2002
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Bian A, Lee J, Barragan D, Andrews JA, BENEFIT-ALS Study Group , Goutman S. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2016 Mar 16; 17 (5-6): 426 - 435.Journal ArticleA randomized, placebo-controlled, double-blind phase IIb trial evaluating the safety and efficacy of tirasemtiv in patients with amyotrophic lateral sclerosis
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Cudkowicz ME, Hardiman O, Cockcroft BM, Lee JH, Malik FI, Meng L, Rudnicki SA, Wolff AA, Andrews JA, VITALITY-ALS Study Group , Goutman S. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2019 Jul 14; ((0)): 1 - 11.Journal ArticleA phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis
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Paganoni S, Macklin EA, Hendrix S, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson T, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S, Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal NA, Pattee GL, ANdres PL, Babu S, Chase M, Dagostino D, Dickson SP, Ellison N, Hall M, Hendrix K, Kittle G, McGovern M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J, Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D, Cudkowicz ME. New England Journal of Medicine, 2020 Sep; 383 ((10)): 919 - 930.Journal ArticleTrial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis
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Goutman S, Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Maurico EA, Baloh RH, Simmons Z, Pothier L, Kassis SB, La T, Hall M, Evora A, Klements D, Hurtado A, Pereira JD, Koh J, Celnik PA, Chaudhry V, Gable K, Juel VC, Phielipp N, Marei A, Rosenquist P, Meehan S, Oskarsson B, Lewis RA, Kaur D, Kiskinis E, Woolf CJ, Eggan K, Weiss MD, Berry JD, David WS, Davila-Perez P, Camprodon JA, Pascual-Leone A, Kiernan MC, Shefner JM, Atassi N, Cudkowicz ME. JAMA Neurology, 2021 Feb; 78 ((2)): 186 - 196.Journal Article: Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial
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Goutman S, Weiss MD, Macklin EA, McIlduff CE, Vucic S, Kiernan MC, Goutman S, Goyal NA, Rutkove SB, Ladha SS, Chen I-HA, Harms MB, Brannagan TH, Lacomis D, Zovlpvoc S, Ma M, Wang LH, Simmons Z, Rivner MH, Shefner JM, Cudkowicz ME, Atassi N, Mexiletine-2 ALS Study Group . Muscle and Nerve, 2021 Mar; 63 (3): 371 - 383.Journal ArticleEffects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial
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Goutman S, Shefner JM, Andrews JA, Genge A , Jackson C , Lechtzin N , Miller TM , Cockroft BM , Meng L , Wei J , Wolff AA , Malik FI , Bodkin C , Brooks BR , Caress J , Dionne A , Fee D , Goyal NA , Hardiman O , Hayat G , Heiman-Patterson T , Heitzman D , Henderson RD , Johnston W , Karam C , Kiernan MC , Kolb SJ , Korngut L , Ladha S , Matte G , Mora JS , Needham M , Oskarsson B , Pattee GL , Pioro EP , Pulley M , Quan D , Rezania K , Schellenberg KL , Schultz D , Shoesmith C , Simmons Z , Statland J , Sultan S , Swenson A , Berg LH V D , Vu T , Vucic S , Weiss M , Whyte-Rayson A , Wymer J , Zinman L , Rudnicki SA . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2020 Sep; 22 (3-4): 287 - 299.Journal ArticleA Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS
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Goutman SA, Boss J, Jang DG, Piecuch C, Farid H, Batra M, Mukherjee B, Feldman EL, Batterman SA. J Neurol Sci, 2024 Jan 23; 457: 122899Journal ArticleAvocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study.
DOI:10.1016/j.jns.2024.122899 PMID: 38278093 -
Murdock B, Zhao B, Raue K, Famie J, Piecuch C, Feldman EL, Zhao L, Goutman S. Journal of the Neurological Sciences, 2023 Dec; 455: 121711Journal ArticleChange in peripheral immunity precede amyotrophic lateral sclerosis progression
DOI:10.1016/j.jns.2023.121711
Department News
New grants support six projects with 'ambitious goal’ of preventing ALS
Department News
The ALS Association grants nearly $5M to boost clinical trial capacity and speed