Daniel Orringer, M.D.

Daniel Orringer, M.D.

Adjunct Assistant Professor, Neurosurgery


Dr. Daniel Orringer received his BA in molecular and cell biology from Cornell University where he graduated magna cum laude. He earned an MD from the Ohio State University and completed his residency at the University of Michigan. After a fellowship in neurosurgical oncology at the Brigham and Women’s Hospital and Harvard Medical School, Dr. Orringer joined the faculty at the University of Michigan. In addition to his clinical duties, Dr. Orringer acts as an advisor to Fast Forward Medical Innovation, a U-M Medical School initiative dedicated to creating a rich environment for improving the care of patients through innovation. He lives in Ann Arbor with his wife and two children.  

Areas of Interest

Dr. Orringer specializes in the care of tumors of the brain and spinal cord. His primary clinical interest is the care of tumors in the regions of the brain that are essential for motor and language function. Dr. Orringer’s focus is on ensuring that his patients will enjoy the best possible quality of life after surgery. To achieve optimal outcome, Dr. Orringer draws on his expertise in the application of state-of-the-art imaging  techniques to visualize and remove tumor, while sparing healthy tissue. Dr. Orringer is dedicated to a multi-disciplinary approach to the care of brain tumor patients, drawing on the expertise of his colleagues in the fields of neurology, neuro-oncology, neuropathology, neuroradiology and speech and language pathology.  

Clinical Interests

Dr. Orringer’s research is in the development of an optical method called stimulated Raman scattering microscopy, which reveals tumor during surgery that may not be visible to the naked eye. He was the first physician to perform stimulated Raman scattering microscopy in an operating room and is leading studies to demonstrate how this technique can be used to improve the safety and accuracy of brain tumor surgery. He directs the Translational Molecular Imaging Laboratory in the Department of Neurosurgery at the University of Michigan and collaborates closely with partners in industry and academia across the country.

Dr. Orringer’s work has been featured on the cover of Science Translational Medicine. He is the recipient of numerous grants from the National Institutes of Health, including a bioengineering research partnership R01 from the National Institute of Biomedical Imaging and Bioengineering and a direct to Phase 2 Small Business Innovation Research grant from the National Cancer Institute. Dr. Orringer’s work has received recognition from The Congress of Neurological Surgeons, American Association of Neurological Surgeons and American Academy of Neurological Surgeons for his work in the field of molecular imaging. He recently was awarded the 2016 Andrew Parsa Young Investigator Basic/Translational Research Award by the Society for Neuro-Oncology.