Parag Patil, M.D. Ph.D. Publications


Anterior lead location predicts verbal fluency decline following STN-DBS in Parkinson's disease.

Greif TR, Askari A, Cook Maher A, Patil PG, Persad C.
Parkinsonism Relat Disord. 2021 Oct 14;92:36-40.
doi: 10.1016/j.parkreldis.2021.10.012

G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy. 

Alghamri MS, McClellan BL, Avvari RP, Thalla R, Carney S, Hartlage MS, Haase S, Ventosa M, Taher A, Kamran N, Zhang L, Faisal SM, Núñez FJ, Garcia-Fabiani MB, Al-Holou WN, Orringer D, Hervey-Jumper S, Heth J, Patil PG, Eddy K, Merajver SD, Ulintz PJ, Welch J, Gao C, Liu J, Núñez G, Hambardzumyan D, Lowenstein PR, Castro MG.
Sci Adv. 2021 Oct;7(40):eabh3243.
doi: 10.1126/sciadv.abh3243

Real-time linear prediction of simultaneous and independent movements of two finger groups using an intracortical brain-machine interface. 

Nason SR, Mender MJ, Vaskov AK, Willsey MS, Ganesh Kumar N, Kung TA, Patil PG, Chestek CA.
Neuron. 2021 Sep 3:S0896-6273(21)00604-8.
doi: 10.1016/j.neuron.2021.08.009

Classifier Using Pontine Radial Diffusivity and Symptom Duration Accurately Predicts Recurrence of Trigeminal Neuralgia After Microvascular Decompression: A Pilot Study and Algorithm Description. 

Willsey MS, Mossner JM, Chestek CA, Sagher O, Patil PG.
Neurosurgery. 2021 Aug 12:nyab292.
doi: 10.1093/neuros/nyab292

Restoring upper extremity function with brain-machine interfaces.

Nason SR, Mender MJ, Letner JG, Chestek CA, Patil PG.
Int Rev Neurobiol. 2021;159:153-186.
doi: 10.1016/bs.irn.2021.06.001

Atlas-independent, N-of-1 tissue activation modeling to map optimal regions of subthalamic deep brain stimulation for Parkinson disease.

Malaga KA, Costello JT, Chou KL, Patil PG.
Neuroimage Clin. 2021;29:102518.
doi: 10.1016/j.nicl.2020.102518

Neural Dynamics in Primate Cortex During Exposure to Subanesthetic Concentrations of Nitrous Oxide. 

Willsey MS, Nu CS, Nason SR, Schroeder KE, Hutchison BC, Welle EJ, Patil PG, Mashour GA, Chestek CA.
eNeuro. 2021 Jun 16:ENEURO.0479-20.2021.
doi: 10.1523/ENEURO.0479-20.2021

Stimulation of zona incerta selectively modulates pain in humans.

Lu CW, Harper DE, Askari A, Willsey MS, Vu PP, Schrepf AD, Harte SE, Patil PG.
Sci Rep. 2021 Apr 26;11(1):8924.
doi: 10.1038/s41598-021-87873-w

Delayed Dopamine Agonist Withdrawal Syndrome After Deep Brain Stimulation for Parkinson Disease.

Jackowiak EM, Chou KL, Patil PG, Levin E, Leventhal D.
Neurol Clin Pract. 2021 Feb;11(1):e35-e36.
doi: 10.1212/CPJ.0000000000000762

Quantitative Sensory Testing of Spinal Cord and Dorsal Root Ganglion Stimulation in Chronic Pain Patients.

Sankarasubramanian V, Chiravuri S, Mirzakhalili E, Anaya CJ, Scott JR, Brummett CM, Clauw DJ, Patil PG, Harte SE, Lempka SF.
Neuromodulation. 2021 Jan 20.
doi: 10.1111/ner.13329


Comparison of signal decomposition techniques for analysis of human cortical signals.

Duraivel S, Rao AT, Lu CW, Bentley JN, Stacey WC, Chestek CA, Patil PG.
J Neural Eng. 2020 Oct 13;17(5):056014.
doi: 10.1088/1741-2552/abb63b

The impact of dispositional optimism and depression on post-operative motor functioning following deep brain stimulation surgery for Parkinson's disease.

Ray H, Cook Maher A, MacKenzie W, Zeitlin L, Chou KL, Patil PG, Persad CC.
Parkinsonism Relat Disord. 2020 Oct 6;81:41-44.
doi: 10.1016/j.parkreldis.2020.10.012

A low-power band of neuronal spiking activity dominated by local single units improves the performance of brain-machine interfaces.

Nason SR, Vaskov AK, Willsey MS, Welle EJ, An H, Vu PP, Bullard AJ, Nu CS, Kao JC, Shenoy KV, Jang T, Kim HS, Blaauw D, Patil PG, Chestek CA.
Nat Biomed Eng. 2020 Oct;4(10):973-983.
doi: 10.1038/s41551-020-0591-0

Distinct perceptive pathways selected with tonic and bursting patterns of thalamic stimulation.

Willsey MS, Lu CW, Nason SR, Malaga KA, Lempka SF, Chestek CA, Patil PG.
Brain Stimul. 2020 Sep-Oct;13(5):1436-1445.
DOI: 10.1016/j.brs.2020.07.007

Magnetic resonance imaging of human neural stem cells in rodent and primate brain.

McGinley LM, Willsey MS, Kashlan ON, Chen KS, Hayes JM, Bergin IL, Mason SN, Stebbins AW, Kwentus JF, Pacut C, Kollmer J, Sakowski SA, Bell CB 3rd, Chestek CA, Murphy GG, Patil PG, Feldman EL.
Stem Cells Transl Med. 2020 Aug 25.
DOI: 10.1002/sctm.20-0126

Localization of motor and verbal fluency effects in subthalamic DBS for Parkinson's disease.

Mossner JM, Chou KL, Maher AH, Persad CC, Patil PG.
Parkinsonism Relat Disord. 2020 Aug 21;79:55-59.
DOI: 10.1016/j.parkreldis.2020.08.023

Correspondence of optimal stimulation and beta power varies regionally in STN DBS for Parkinson disease.

Lu CW, Chou KL, Patil PG.
Parkinsonism Relat Disord. 2020 Aug 11;78:124-128.
DOI: 10.1016/j.parkreldis.2020.08.008

A low-power band of neuronal spiking activity dominated by local single units improves the performance of brain-machine interfaces.

Nason SR, Vaskov AK, Willsey MS, Welle EJ, An H, Vu PP, Bullard AJ, Nu CS, Kao JC, Shenoy KV, Jang T, Kim HS, Blaauw D, Patil PG, Chestek CA.
Nat Biomed Eng. 2020 Jul 27.
DOI: 10.1038/s41551-020-0591-0

Caregiver burden worsens in the second year after subthalamic nucleus deep brain stimulation for Parkinson's disease.

Jackowiak E, Maher AC, Persad C, Kotagal V, Wyant K, Heston A, Patil PG, Chou KL.
Parkinsonism Relat Disord. 2020 Jul 4;78:4-8.
DOI: 10.1016/j.parkreldis.2020.06.036

Estimating Risk for Future Intracranial, Fully Implanted, Modular Neuroprosthetic Systems: A Systematic Review of Hardware Complications in Clinical Deep Brain Stimulation and Experimental Human Intracortical Arrays.

Bullard AJ, Hutchison BC, Lee J, Chestek CA, Patil PG.
Neuromodulation. 2020 Jun;23(4):411-426.
DOI: 10.1111/ner.13069

High density microelectrode recording predicts span of therapeutic tissue activation volumes in subthalamic deep brain stimulation for Parkinson disease.

Lu CW, Malaga KA, Chou KL, Chestek CA, Patil PG.
Brain Stimul. 2020 Mar-Apr;13(2):412-419.
DOI: 10.1016/j.brs.2019.11.013

Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks. 

Hollon TC, Pandian B, Adapa AR, Urias E, Save AV, Khalsa SSS, Eichberg DG, D'Amico RS, Farooq ZU, Lewis S, Petridis PD, Marie T, Shah AH, Garton HJL, Maher CO, Heth JA, McKean EL, Sullivan SE, Hervey-Jumper SL, Patil PG, Thompson BG, Sagher O, McKhann GM 2nd, Komotar RJ, Ivan ME, Snuderl M, Otten ML, Johnson TD, Sisti MB, Bruce JN, Muraszko KM, Trautman J, Freudiger CW, Canoll P, Lee H, Camelo-Piragua S, Orringer DA.
Nat Med. 2020 Jan;26(1):52-58. 
DOI: 10.1038/s41591-019-0715-9


Subthalamic nucleus deep brain stimulation improves dyskinesias in Parkinson's disease beyond levodopa reduction.

Mossner JM, Patil PG, Chou KL.
J Neural Transm (Vienna). 2019 Nov;126(11):1479-1483.
DOI: 10.1007/s00702-019-02076-y

Diffusion tensor imaging reveals microstructural differences between subtypes of trigeminal neuralgia.

Willsey MS, Collins KL, Conrad EC, Chubb HA, Patil PG.
J Neurosurg. 2019 Jul 19:1-7.
DOI: 10.3171/2019.4.JNS19299

The Deep Brain Stimulation "Twiddler Syndrome".

Jackowiak E, Patil PG, Chou KL.
JAMA Neurol. 2019 May 1;76(5):620.
DOI: 10.1001/jamaneurol.2019.0691

Author's Response to Letter to the Editor: Noninvasive Intracranial Pressure Assessment in Acute Liver Failure.

Rajajee V, Williamson CA, Fontana RJ, Courey AJ, Patil PG.
Neurocrit Care. 2019 Apr;30(2):497.
DOI: 10.1007/s12028-019-00681-z

Design and testing of a 96-channel neural interface module for the Networked Neuroprosthesis system.

Bullard AJ, Nason SR, Irwin ZT, Nu CS, Smith B, Campean A, Peckham PH, Kilgore KL, Willsey MS, Patil PG, Chestek CA.
Bioelectron Med. 2019 Feb 15;5:3.
DOI: 10.1186/s42234-019-0019-x

Designing Next-Generation Local Drug Delivery Vehicles for Glioblastoma Adjuvant Chemotherapy: Lessons from the Clinic.

Tabet A, Jensen MP, Parkins CC, Patil PG, Watts C, Scherman OA.
Adv Healthc Mater. 2019 Feb;8(3):e1801391.
DOI: 10.1002/adhm.201801391

Objective Measures to Characterize the Physiological Effects of Spinal Cord Stimulation in Neuropathic Pain: A Literature Review.

Sankarasubramanian V, Harte SE, Chiravuri S, Harris RE, Brummett CM, Patil PG, Clauw DJ, Lempka SF.
Neuromodulation. 2019 Feb;22(2):127-148.
DOI: 10.1111/ner.12804

Parag Patil, M.D.

Parag G. Patil, M.D., Ph.D.

Associate Professor, Neurological Surgery
Associate Professor, Neurology
Associate Professor, Anesthesiology
Associate Professor of Biomedical Engineering, College of Engineering