Venkatakrishna Rajajee, M.B.B.S. Publications

2022

Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial.

Bösel J, Niesen WD, Salih F, Morris NA, Ragland JT, Gough B, Schneider H, Neumann JO, Hwang DY, Kantamneni P, James ML, Freeman WD, Rajajee V, Rao CV, Nair D, Benner L, Meis J, Klose C, Kieser M, Suarez JI, Schönenberger S, Seder DB; SETPOINT2 and the IGNITE Study Groups.
JAMA. 2022 May 17;327(19):1899-1909.
doi: 10.1001/jama.2022.4798

Perceptions Regarding the SARS-CoV-2 Pandemic's Impact on Neurocritical Care Delivery: Results From a Global Survey.

Lele AV, Wahlster S, Alunpipachathai B, Awraris Gebrewold M, Chou SH, Crabtree G, English S, Der-Nigoghossian C, Gagnon DJ, Kim-Tenser M, Karanjia N, Kirkman MA, Lamperti M, Livesay SL, Mejia-Mantilla J, Melmed K, Prabhakar H, Tumino L, Venkatasubba Rao CP, Udy AA, Videtta W, Moheet AM; NCC-COVID Study Collaborators.
J Neurosurg Anesthesiol. 2022 Apr 1;34(2):209-220.
doi: 10.1097/ANA.0000000000000825

Incidence, Predictors and Outcomes of Delirium in Critically Ill Patients With COVID-19. 

Williamson CA, Faiver L, Nguyen AM, Ottenhoff L, Rajajee V.
Neurohospitalist. 2022 Jan;12(1):31-37.
doi: 10.1177/19418744211034815

A 57 Year-Old Man With HIV Presenting With Severe Headache and Progressive Weakness.

Nguyen AM, Decker JA, Dupuis JE, Little AA, Ottenhoff LD, Rajajee V, Sheehan KM, Williamson CA.
Neurohospitalist. 2022 Jan;12(1):171-176.
doi: 10.1177/1941874420980630

2021

Correction to: Neurocritical Care Society Guidelines Update: Lessons from a Decade of GRADE Guidelines.

Madden LK, Rajajee V, Human T, Wainwright MS, Guanci M, Mainali S, Rowe S, McLaughlin D, Lunde J, Lele A, Fried H.
Neurocrit Care. 2021 Dec 7.
doi: 10.1007/s12028-021-01411-0

Screening Computed Tomography Angiography to Identify Patients at Low Risk for Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage. 

Nguyen AM, Williamson CA, Pandey AS, Sheehan KM, Rajajee V.
Front Neurol. 2021 Nov 12;12:740241.
doi: 10.3389/fneur.2021.740241

Neurocritical Care Society Guidelines Update: Lessons from a Decade of GRADE Guidelines.

Madden LK, Rajajee V, Human T, Wainwright MS, Guanci M, Mainali S, Rowe S, McLaughlin D, Lunde J, Lele A, Fried H.
Neurocrit Care. 2021 Nov 2:1–10.
doi: 10.1007/s12028-021-01375-1

One-Year Functional, Cognitive, and Psychological Outcomes Following the Use of Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019: A Prospective Study. 

Rajajee V, Fung CM, Seagly KS, Park PK, Raghavendran K, Machado-Aranda DA, Scott JW, Delano MJ, Abou El Ela ASAA, Haft JW, Williamson CA, McSparron JI, Blank R, Napolitano LM.
Crit Care Explor. 2021 Sep 10;3(9):e0537.
doi: 10.1097/CCE.0000000000000537

Tracheostomy for COVID-19 respiratory failure: timing, ventilatory characteristics, and outcomes.

Farlow JL, Park PK, Sjoding MW, Kay SG, Blank R, Malloy KM, Washer L, Napolitano LM, Rajajee V, Brenner MJ, Chinn SB, De Cardenas J.
J Thorac Dis. 2021 Jul;13(7):4137-4145.
doi: 10.21037/jtd-21-10

Safety and Efficacy of 23.4% Sodium Chloride Administered via Peripheral Venous Access for the Treatment of Cerebral Herniation and Intracranial Pressure Elevation. 

Faiver L, Hensler D, Rush SC, Kashlan O, Williamson CA, Rajajee V.
Neurocrit Care. 2021 Jun 25.
doi: 10.1007/s12028-021-01248-7

23.4% Hypertonic Saline: A Tactical Option for the Management of Severe Traumatic Brain Injury With Impending or Ongoing Herniation.

DeSoucy ES, Cacic K, Staak BP, Petersen CD, van Wyck D, Rajajee V, Dorsch J, Rush SC.
J Spec Oper Med. 2021 Summer;21(2):25-28
PMID: 34105117

Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage.

Askenase MH, Goods BA, Beatty HE, Steinschneider AF, Velazquez SE, Osherov A, Landreneau MJ, Carroll SL, Tran TB, Avram VS, Drake RS, Gatter GJ, Massey JA, Karuppagounder SS, Ratan RR, Matouk CC, Sheth KN, Ziai WC, Parry-Jones AR, Awad IA, Zuccarello M, Thompson RE, Dawson J, Hanley DF, Love JC, Shalek AK, Sansing LH; MISTIE III Consortium; ICHseq investigators; ICHseq Investigators MISTIE III Investigators.
Sci Immunol. 2021 Feb 19;6(56):eabd6279.
doi: 10.1126/sciimmunol.abd6279

Length of Stay Beyond Medical Readiness in a Neurosurgical Patient Population and Associated Healthcare Costs. 

Linzey JR, Foshee R, Moriguchi F, Adapa AR, Koduri S, Kahn EN, Williamson CA, Sheehan K, Rajajee V, Thompson BG, Muraszko KM, Pandey AS.
Neurosurgery. 2021 Feb 16;88(3):E259-E264.
doi: 10.1093/neuros/nyaa535

Volumetric quantification of aneurysmal subarachnoid hemorrhage independently predicts hydrocephalus and seizures. 

Daou BJ, Khalsa SSS, Anand SK, Williamson CA, Cutler NS, Aaron BL, Srinivasan S, Rajajee V, Sheehan K, Pandey AS.
J Neurosurg. 2021 Feb 5:1-9. 
doi: 10.3171/2020.8.JNS201273

Novel Algorithm for Automated Optic Nerve Sheath Diameter Measurement Using a Clustering Approach.

Rajajee V, Soroushmehr R, Williamson CA, Najarian K, Gryak J, Awad A, Ward KR, Tiba MH.
Mil Med. 2021 Jan 25;186(Suppl 1):496-501.
doi: 10.1093/milmed/usaa231

2020

A Prospective Study of Optic Nerve Ultrasound for the Detection of Elevated Intracranial Pressure in Severe Traumatic Brain Injury.

Agrawal D, Raghavendran K, Zhao L, Rajajee V.
Crit Care Med. 2020 Oct 13.
doi: 10.1097/CCM.0000000000004689

Use of a Novel Negative-Pressure Tent During Bedside Tracheostomy in COVID-19 Patients.

Rajajee V, Williamson CA.
Neurocrit Care. 2020 Oct;33(2):597-603.
DOI: 10.1007/s12028-020-01068-1

Case Series: Evidence of Borderzone Ischemia in Critically-Ill COVID-19 Patients Who "Do Not Wake Up".

Pirau L, Ottenhoff L, Williamson CA, Ahmad SN, Wabl R, Nguyen A, Faiver L, Rajajee V.
Front Neurol. 2020 Sep 23;11:964.
doi: 10.3389/fneur.2020.00964

Novel Algorithm for Automated Optic Nerve Sheath Diameter Measurement Using a Clustering Approach.

Rajajee V, Soroushmehr R, Williamson CA, Najarian K, Gryak J, Awad A, Ward KR, Tiba MH.
Mil Med. 2020 Aug 22:usaa231.
DOI: 10.1093/milmed/usaa231

Late Surgical Start Time and the Effect on Rates of Complications in a Neurosurgical Population: A Prospective Longitudinal Analysis.

Linzey JR, Foshee RL, Fiestan GO, Srinivasan S, Mossner JM, Rajajee V, Sullivan SE, Thompson BG, Muraszko KM, Pandey AS.  
World Neurosurg. 2020 Aug;140:e328-e342. 
DOI: 10.1016/j.wneu.2020.05.081

Brain Autopsy Findings in Adult Extracorporeal Membrane Oxygenation: Precipitating Event or Extracorporeal Membrane Oxygenation Treatment? Need More Data…

Napolitano LM, Rajajee V.
Crit Care Med. 2020 Jun;48(6):936-937.
DOI: 10.1097/CCM.0000000000004319

The Predictive Value of the HOSPITAL Score and LACE Index for an Adult Neurosurgical Population: A Prospective Analysis.

Linzey JR, Foshee RL, Srinivasan S, Fiestan GO, Mossner JM, Gemmete JJ, Burke JF, Sheehan KM, Rajajee V, Pandey AS.
World Neurosurg. 2020 May;137:e166-e175.
DOI: 10.1016/j.wneu.2020.01.117

Emergency Neurological Life Support: Fourth Edition, Updates in the Approach to Early Management of a Neurological Emergency.

Venkatasubramanian C, Lopez GA, O'Phelan KH; ENLS Writing Group.
Neurocrit Care. 2020 Apr;32(2):636-640.
doi: 10.1007/s12028-019-00810-8

Global Survey of Outcomes of Neurocritical Care Patients: Analysis of the PRINCE Study Part 2.

Venkatasubba Rao CP, Suarez JI, Martin RH, Bauza C, Georgiadis A, Calvillo E, Hemphill JC 3rd, Sung G, Oddo M, Taccone FS, LeRoux PD; PRINCE Study Investigators.
Neurocrit Care. 2020 Feb;32(1):88-103.
DOI: 10.1007/s12028-019-00835-z

Worldwide Organization of Neurocritical Care: Results from the PRINCE Study Part 1.

Suarez JI, Martin RH, Bauza C, Georgiadis A, Venkatasubba Rao CP, Calvillo E, Hemphill JC 3rd, Sung G, Oddo M, Taccone FS, LeRoux PD; PRINCE Study Investigators.
Neurocrit Care. 2020 Feb;32(1):172-179.
DOI: 10.1007/s12028-019-00750-3

Validation of the LACE Index (Length of Stay, Acuity of Admission, Comorbidities, Emergency Department Use) in the Adult Neurosurgical Patient Population.

Linzey JR, Nadel JL, Wilkinson DA, Rajajee V, Daou BJ, Pandey AS.
Neurosurgery. 2020 Jan 1;86(1):E33-E37.
DOI: 10.1093/neuros/nyz300

2019

Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.

Johnston KC, Bruno A, Pauls Q, Hall CE, Barrett KM, Barsan W, Fansler A, Van de Bruinhorst K, Janis S, Durkalski-Mauldin VL; Neurological Emergencies Treatment Trials Network and the SHINE Trial Investigators.
JAMA. 2019 Jul 23;322(4):326-335.
Erratum in: JAMA. 2019 Nov 5;322(17):1718.
DOI: 10.1001/jama.2019.9346

Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis.

Fernando SM, Tran A, Cheng W, Rochwerg B, Taljaard M, Kyeremanteng K, English SW, Sekhon MS, Griesdale DEG, Dowlatshahi D, McCredie VA, Wijdicks EFM, Almenawer SA, Inaba K, Rajajee V, Perry JJ.
BMJ. 2019 Jul 24;366:l4225.
DOI: 10.1136/bmj.l4225

Subarachnoid Hemorrhage and Therapy Formerly Known as "Triple-H" - New Directions.

Rajajee V, Pandey AS, Williamson CA.
World Neurosurg. 2019 Jul;127:500-501.
DOI: 10.1016/j.wneu.2019.04.212

Critical Care Ultrasound Should Be a Priority First-Line Assessment Tool in Neurocritical Care.

Rajajee V, Díaz-Gómez JL.
Crit Care Med. 2019 Jun;47(6):833-836.
DOI: 10.1097/CCM.0000000000003712

Author's Response to Letter to the Editor: Noninvasive Intracranial Pressure Assessment in Acute Liver Failure.

Rajajee V, Williamson CA, Fontana RJ, Courey AJ, Patil PG.
Neurocrit Care. 2019 Apr;30(2):497.
DOI: 10.1007/s12028-019-00681-z


Venkatakrishna Rajajee, M.B.B.S.

Clinical Professor, Neurological Surgery
Clinical Professor, Neurology
Medical Director, Neurocritical Care
Co-Director, The Comprehensive Stroke Center
734-936-8224