Ya Hua, M.D. Publications


Iron-Induced Hydrocephalus: the Role of Choroid Plexus Stromal Macrophages.

Bian C, Wan Y, Koduri S, Hua Y, Keep RF, Xi G.
Transl Stroke Res. 2022 May 11.
doi: 10.1007/s12975-022-01031-6

A timeline of oligodendrocyte death and proliferation following experimental subarachnoid hemorrhage.

Peng K, Koduri S, Ye F, Yang J, Keep RF, Xi G, Hua Y.
CNS Neurosci Ther. 2022 Jun;28(6):842-850.
doi: 10.1111/cns.13812

Too big, too small: selecting hematoma sizes for inclusion in intracerebral hemorrhage-deferoxamine trials. 

Ye F, Wan Y, Koduri S, Holste KG, Keep RF, Hua Y, Xi G.
Transl Stroke Res. 2022 Mar 28. 
doi: 10.1007/s12975-022-01013-8

Delayed Minocycline Treatment Ameliorates Hydrocephalus Development and Choroid Plexus Inflammation in Spontaneously Hypertensive Rats. 

Hao X, Ye F, Holste KG, Hua Y, Garton HJL, Keep RF, Xi G.
Int J Mol Sci. 2022 Feb 19;23(4):2306. 
doi: 10.3390/ijms23042306

The Fate of Erythrocytes after Cerebral Hemorrhage.

Xia F, Keep RF, Ye F, Holste KG, Wan S, Xi G, Hua Y.
Transl Stroke Res. 2022 Jan 23.
doi: 10.1007/s12975-021-00980-8


The Two Faces of Estrogen in Experimental Hemorrhagic Stroke

Koduri S, Keep RF, Hua Y, Chaudhary N, Pandey AS, Xi G.
Transl Stroke Res. 2021 Sep 16.
doi: 10.1007/s12975-021-00942-0

Impact of sex differences on thrombin-induced hydrocephalus and white matter injury: the role of neutrophils. 

Peng K, Koduri S, Xia F, Gao F, Hua Y, Keep RF, Xi G.
Fluids Barriers CNS. 2021 Aug 16;18(1):38.
doi: 10.1186/s12987-021-00273-0

Role of Complement Component 3 in Early Erythrolysis in the Hematoma After Experimental Intracerebral Hemorrhage. 

Wang M, Xia F, Wan S, Hua Y, Keep RF, Xi G.
Stroke. 2021 Jun 28:STROKEAHA121034372.
doi: 10.1161/STROKEAHA.121.034372

Acute T2*-Weighted Magnetic Resonance Imaging Detectable Cerebral Thrombosis in a Rat Model of Subarachnoid Hemorrhage. 

Zhang J, Peng K, Ye F, Koduri S, Hua Y, Keep RF, Xi G.
Transl Stroke Res. 2021 Jun 2.
doi: 10.1007/s12975-021-00918-0

Acute micro-thrombosis after subarachnoid hemorrhage: A new therapeutic target? 

Ye F, Keep RF, Hua Y, Garton HJ, Xi G.
J Cereb Blood Flow Metab. 2021 May 17:271678X211013595.
doi: 10.1177/0271678X211013595

CD47 blocking antibody accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage.

Ye F, Hua Y, Keep RF, Xi G, Garton HJL.
Neurobiol Dis. 2021 May 1:105384.
doi: 10.1016/j.nbd.2021.105384

Hydrocephalus Induced by Intraventricular Peroxiredoxin-2: The Role of Macrophages in the Choroid Plexus. 

Chen T, Tan X, Xia F, Hua Y, Keep RF, Xi G.
Biomolecules. 2021 Apr 29;11(5):654.
doi: 10.3390/biom11050654

Hydrocephalus Following Experimental Subarachnoid Hemorrhage in Rats with Different Aerobic Capacity. 

Toyota Y, Shishido H, Ye F, Koch LG, Britton SL, Garton HJL, Keep RF, Xi G, Hua Y.
Int J Mol Sci. 2021 Apr 26;22(9):4489.
doi: 10.3390/ijms22094489

The role of complement in brain injury following intracerebral hemorrhage: A review.

Holste K, Xia F, Garton HJL, Wan S, Hua Y, Keep RF, Xi G.
Exp Neurol. 2021 Feb 19:113654.
doi: 10.1016/j.expneurol.2021.113654

Ultra-Early Cerebral Thrombosis Formation After Experimental Subarachnoid Hemorrhage Detected on T2* Magnetic Resonance Imaging.

Wang Z, Chen J, Toyota Y, Keep RF, Xi G, Hua Y.
Stroke. 2021 Feb 4:STROKEAHA120032397.
doi: 10.1161/STROKEAHA.120.032397


Role of lipocalin-2 in extracellular peroxiredoxin 2-induced brain swelling, inflammation and neuronal death. 

Zhang J, Novakovic N, Hua Y, Keep RF, Xi G.
Exp Neurol. 2020 Oct 29;335:113521. 
doi: 10.1016/j.expneurol.2020.113521

Intra-hematomal White Matter Tracts Act As a Scaffold for Macrophage Infiltration After Intracerebral Hemorrhage.

Chen J, Koduri S, Dai S, Toyota Y, Hua Y, Chaudhary N, Pandey AS, Keep RF, Xi G.
Transl Stroke Res. 2020 Oct 22.
doi: 10.1007/s12975-020-00870-5

White matter T2 hyperintensities and blood-brain barrier disruption in the hyperacute stage of subarachnoid hemorrhage in male mice: The role of lipocalin-2. 

Toyota Y, Wei J, Xi G, Keep RF, Hua Y.
CNS Neurosci Ther. 2019 Oct;25(10):1207-1214. 
doi: 10.1111/cns.13221

Activation of epiplexus macrophages in hydrocephalus caused by subarachnoid hemorrhage and thrombin. 

Wan Y, Hua Y, Garton HJL, Novakovic N, Keep RF, Xi G.
CNS Neurosci Ther. 2019 Oct;25(10):1134-1141. 
doi: 10.1111/cns.13203

Multinucleated Giant Cells in Experimental Intracerebral Hemorrhage.

Wei J, Wang M, Jing C, Keep RF, Hua Y, Xi G.
Transl Stroke Res. 2020 Oct;11(5):1095-1102
DOI: 10.1007/s12975-020-00790-4

The Role of Thrombin in Brain Injury After Hemorrhagic and Ischemic Stroke.

Ye F, Garton HJL, Hua Y, Keep RF, Xi G.
Transl Stroke Res. 2020 Sep 29.
DOI: 10.1007/s12975-020-00855-4

Mechanisms of Post-Hemorrhagic Stroke Hydrocephalus Development: The Role of Kolmer Epiplexus Cells. 

Koduri S, Daou B, Hua Y, Keep R, Xi G, Pandey AS.
World Neurosurg. 2020 Sep 28;144:256-257. 
doi: 10.1016/j.wneu.2020.09.121

Cerebrospinal Fluid from Aneurysmal Subarachnoid Hemorrhage Patients Leads to Hydrocephalus in Nude Mice.

Wan S, Wei J, Hua Y, Koduri S, Keep RF, Xi G, Pandey AS.
Neurocrit Care. 2020 Jul 1.
DOI: 10.1007/s12028-020-01031-0

CD47 Blocking Antibody Accelerates Hematoma Clearance After Intracerebral Hemorrhage in Aged Rats.

Tao C, Keep RF, Xi G, Hua Y.
Transl Stroke Res. 2020 Jun;11(3):541-551.
DOI: 10.1007/s12975-019-00745-4

Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage.

Tan X, Chen J, Keep RF, Xi G, Hua Y.
Stroke. 2020 May;51(5):1578-1586
DOI: 10.1161/STROKEAHA.119.028672

Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.

Bian L, Zhang J, Wang M, Keep RF, Xi G, Hua Y.
Transl Stroke Res. 2020 Apr;11(2):288-295. 
DOI: 10.1007/s12975-019-00714-x

Effects of aging on hydrocephalus after intraventricular hemorrhage.

Wan Y, Gao F, Ye F, Yang W, Hua Y, Keep RF, Xi G.
Fluids Barriers CNS. 2020 Feb 28;17(1):8.
DOI: 10.1186/s12987-020-0169-y

Ya Hua, M.D.

Research Professor, Neurosurgery