Dr. Cagri Besirli

Cagri G. Besirli, MD, PhD

Assistant Professor, Ophthalmology and Visual Sciences
Skillman Career Development Professor of Pediatric Ophthalmology
Academic Office: 734-232-8404

Areas of Interest

Research Areas

Research Summary

Molecular mechanisms of photoreceptor cell death and survival during periods of retinal stress

Dr. Besirli's research focuses on the characterization of pathways critical for cell death during retinal stress, including retinal detachment and macular degeneration. Primary focus is given to the identification of individual proteins that regulate intracellular checkpoints important for retinal cell death or survival, with the ultimate goal of developing new therapeutic agents for clinical use. 

Clinical Interests

  • Disease and surgery of the retina and vitreous, including retinal detachment, diabetic retinopathy, age-related macular degeneration, retinal vascular disease, ocular trauma, ocular inflammation, macular and submacular surgery, and surgical management of complex retinal detachment
  • Medical and surgical management of acquired and inherited pediatric retinal disorders, including retinopathy of prematurity (ROP), familial exudative vitreoretinopathy (FEVR), Coats’ disease, retinal detachment, and ocular trauma

Sub-specialty: Retina

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Honors & Awards

2018

  • Clinical Trial, An Open-label, Multi-Centre, Phase I/II Dose Escalation Trial of an Adeno-Associated Virus Vector (AAV2/5-OPTIRPE65) for Gene Therapy of Adults and Children with Retinal Dystrophy associated with Defects in RPE65 (LCA2), MeiraGTx

Credentials

  • Medical and Graduate School - Washington University in St. Louis, 2006
  • Residency - Ophthalmology, Kellogg Eye Center, University of Michigan, 2010
  • Fellowships
    • Retina and Uveitis, Kellogg Eye Center, University of Michigan, 2012
    • Pediatric Vitreoretinal Diseases, Associated Retinal Consultants, Royal Oak, Michigan
  • Board Certification - American Board of Ophthalmology

Published Articles or Reviews

Web Sites