Ernestina Schipani, MD, PhD

Professor, Orthopaedic Surgery
Professor, Internal Medicine/Division of Endocrinology
Professor, Cell and Developmental Biology
University of Michigan
Orthopaedic Research Laboratories
A. Alfred Taubman Biomedical Science Research Building, Room 2007
109 Zina Pitcher Place
Ann Arbor, MI 48109-2200


Ernestina Schipani, M.D., Ph.D. is a Full Professor of Orthopedic Surgery, Medicine and Cell and Developmental Biology at University of Michigan-Medical School.  She earned her M.D. and Ph.D. at St. Anna School of Advanced Studies-University of Pisa, Italy, then did her postdoctoral studies at MGH-Harvard Medical School, where she subsequently rose through the ranks and became Associate Professor. She was recruited to Indiana University-Medical School as a Full Professor of Internal Medicine. Early in her career, Dr. Schipani discovered that gain-of-function mutations of PTHR1 cause Jansen disease. Next, she pioneered the notion that hypoxia-driven pathways control skeletal development. Her laboratory has established novel principles in the broader fields of G-protein coupled receptors and hypoxia biology. She has received numerous national and international recognitions. NIH funds her research as an independent investigator since 1997. She is also ASCI member since 2005. Dr. Schipani has authored more than 150 publications.

Areas of Interest

Dr. Ernestina Schipani's laboratory has a long-standing interest in the study of bone development. Over the years, her laboratory has used cartilage and bone tissues as models to establish important principles in the broader fields of receptor and hypoxia biology. Please visit her lab to find out more about their past major discoveries and current research. Ernestina (Stina) Schipani's Research Lab


Doctorate of Medicine (M.D.) - 1985
Doctorate of Philosophy (Ph.D.) - 1989