The Orthopaedic Research Laboratories (ORL) is a consortium encompassing the molecular, cellular, physiologic, bio-engineering and pre-clinical imaging research of the faculty of the Department of Orthopaedic Surgery at the University of Michigan.

Each faculty member in the ORL maintains an independent research laboratory, and also shares in extensive collaborative space with cutting edge research equipment and resources. The environment provided by faculty, staff and trainees composed of biologists, engineers and clinicians, catalyzes the collaborative research programs focused on improving the treatment or prevention of musculoskeletal disorders and disease.

Facilities and Resources The ORL is housed in the brand new A. Alfred Taubman Biomedical Science Research Building on the campus of the UM Medical School. The facilities and resources in the ORL make it one of the most leading centers for musculoskeletal research in the world.

The facilities and resources include:

  • Advanced microscopy and in vivo fluorescent imaging systems
  • Biomechanics and motion capture facilities
  • Bone and connective tissue mechanical properties testing equipment
  • Cell culture and imaging facilities
  • Engineering and fabrication facilities
  • Histology and tissue embedding and processing facilities
  • Micro- and nano-CT imaging systems
  • Molecular biology equipment
  • X-ray and fluoroscopy equipment


Steven Goldstein, PhD

Professor Emeritus, Mechanical Engineering
Professor Emeritus, Biomedical Engineering
Professor Emeritus, Orthopaedic Surgery
Research Professor Emeritus, Institute of Gerontology

Karl Jepsen, PhD

Associate Chair of Research
Henry Ruppenthal Family Professor, Orthopaedic Surgery and Bioengineering
Professor, Orthopaedic Surgery
Professor, Biomedical Engineering
Glancy Family Scholar

Kenneth Kozloff, PhD

Associate Professor, Orthopaedic Surgery
Associate Professor, Biomedical Engineering

Ernestina Schipani, MD, PhD

Professor, Orthopaedic Surgery
Professor, Internal Medicine
Professor, Cell and Developmental Biology