FSGS Recurrence Collaboration Meeting

Save the Date for FSGS Meeting

 

Please Join Us For the Inaugural Virtual FSGS Recurrence Collaboration Meeting

Please register for the conference at:

https://umich.irisregistration.com/Form/FSGS21

December 13 from 1:00 PM - 5:00 PM EST

December 14 from 8:00 AM - 12:00 PM EST

Questions? Email: FSGSRecurrenceCollab@umich.edu

Program committee:

Agenda

All times are listed in eastern standard time.  You can also download this agenda as a PDF.

This 2-day meeting will focus on the critical problem of Recurrent Focal Segmental Glomerulosclerosis in kidney transplant. The primary objectives of this meeting are to identify and prioritize opportunities to advance our understanding of disease mechanisms, expand the foundation for drug development and expand collaborative research focused FSGS recurrence.

Approach: This meeting will prioritize a robust discussion among participants within each session.

December 13, 2021 

1:00 pm - Welcome and Introductions

Goals of the Collaborative – Debbie Gipson, MD
Donna Martin, MD, Chair, Department of Pediatrics,
CS Mott Children’s Hospital, University of Michigan

1:15 pm - State of the problem (Session Chair: Debbie Gipson, MD)

  • FSGS Recurrence Population Perspective:
    Eloise Salmon, M.D. - University of Michigan 
  • Patient/Family Caregiver Perspective
  • Question and Answer Session

2:00 pm - Use of genetics as a research accelerator for 
FSGS Recurrence [Session Co-Chair: John Sedor, MD
Cleveland Clinic Foundation & Simone Sanna-Cherchi, Columbia University]

  • Pediatric Perspective: Rasheed Gbadegesin, MD, MBBS – Duke University (Children)
  • Insights from Tango: Leonardo Riello, MD, Harvard (Adults)
  • Using genetics to dissect FSGS recurrrance: Simone Sanna-Cherchi, MD, Columbia University
  • Audience - Panel Discussion.

3:15 pm - Break

3:30 pm - Identifying Disease Pathways: Podocyte and Beyond 
[Session Co-Chair: Alessia Fornoni, MD, PhD, University of Miami and Matthias Kretzler, MD
University of Michigan]

  • Molecular Mechanisms of FSGS: SandraMerscher, PhD, University of Miami
  • Mapping Immune Cell Activity in Epithelial Cell Injury in Lupus Nephritis, Paul Hoover, Harvard Medical School
  • Podocyte Dropout and FSGS: Abhijit Naik, MBBS- University of Michigan
  • Audience – Panel Discussion

4:45 pm - Wrap Up

5:00 pm - Conclude

December 14, 2021

8:00 am - Welcome

8:05 am - Identifying Disease Pathways and Modifiers
[Session Co-Chairs: Larry Holzman, MD, University of PA and Rasheed Gbadegesin, MD]

  • HLA Biology: Annette Jackson, Ph.D. - Duke University
  • APOL1 Nephropathy: Opeyemi Ofabisi, MD., Phd - Duke University
  • Audience - Panel Discussion

9:10 am - Exploring Disease Mechanisms: Methodology
[Session Co-Chair: Jonathan Himmelfarb, MD, University of WA and Marina Vivarelli, MD, Ospedale Pediatrico Bambino Gesu]

  • Methods: High sensitivity flow cytometry 
  • Methods: Organoids: Benjamin Freedman, Ph.D., University of Washington, Seattle
  • Methods: Organoids: Jennifer Harder, M.D. - University of Michigan 
  • Methods: Proteomics: Jon Klein, M.D., Ph.D. - University of Louisville
  • Audience - Panel Discussion

10:30 am - Break

10:50 am - Therapy Development & Rare Disease Trial Design [Co-Chair: Howard Trachtman, MD, University of Michigan]

  • Lessons learned from Trials: George Burke, MD, University of Miami
  • Panelists: George Burke, MD, Michelle Rheault, MD, University of MN, Catherine Spino, ScD, University of Michigan, Kelley Kidwell, PhD, University of Michigan
  • Audience - Panel Discussion 

11:40 pm - Next Steps - [ Dr. Debbie Gipson]

NOON - Conclude