Andrew J Alt
Associate Research Scientist, Pharmacology
Associate Research Scientist, Life Sciences Institute
[email protected]

Available to mentor

Andrew J Alt
Associate Research Scientist
  • Recent Publications
  • Recent Publications See All Publications
    • Journal Article
      Identification and validation of G protein-coupled receptors modulating flow-dependent signaling pathways in vascular endothelial cells.
      Qiu D, Xu K, Chung N, Robbins J, Luo R, Lawrence M, He A, Yu F, Alt A, Miller MM, Hangeland J, Feder JN, Seiffert D, Arey BJ. Front Mol Biosci, 2023 10: 1198079 DOI:10.3389/fmolb.2023.1198079
      PMID: 37363403
    • Journal Article
      Finding the Perfect Fit: Conformational Biosensors to Determine the Efficacy of GPCR Ligands.
      Olson KM, Campbell A, Alt A, Traynor JR. ACS Pharmacol Transl Sci, 2022 Sep 9; 5 (9): 694 - 709. DOI:10.1021/acsptsci.1c00256
      PMID: 36110374
    • Journal Article
      Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
      Tsou P-S, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. J Clin Invest, 2022 Jun 1; 132 (11): DOI:10.1172/JCI151827
      PMID: 35439173
    • Journal Article
      Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
      Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. The Journal of clinical investigation, 2022 Jun 1; 132 (11): e151827 - e151827.
    • Journal Article
      Allosteric Modulator Leads Hiding in Plain Site: Developing Peptide and Peptidomimetics as GPCR Allosteric Modulators.
      Olson KM, Traynor JR, Alt A. Front Chem, 2021 9: 671483 DOI:10.3389/fchem.2021.671483
      PMID: 34692635
    • Journal Article
      Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.
      Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li M-H, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR. Proc Natl Acad Sci U S A, 2021 Apr 20; 118 (16): DOI:10.1073/pnas.2000017118
      PMID: 33846240
    • Journal Article
      Identification and biochemical analyses of selective CB2 agonists.
      Scott CE, Tang Y, Alt A, Burford NT, Gerritz SW, Ogawa LM, Zhang L, Kendall DA. Eur J Pharmacol, 2019 Jul 5; 854: 1 - 8. DOI:10.1016/j.ejphar.2019.03.054
      PMID: 30951717
    • Journal Article
      Discovery of Selective Cannabinoid CB2 Receptor Agonists by High-Throughput Screening.
      Ogawa LM, Burford NT, Liao Y-H, Scott CE, Hine AM, Dowling C, Chin J, Power M, Hunnicutt EJ, Emerick VL, Banks M, Zhang L, Gerritz SW, Alt A, Kendall DA. SLAS Discov, 2018 Apr; 23 (4): 375 - 383. DOI:10.1177/2472555217748403
      PMID: 29257918
    Featured News & Stories
    Department News
    Dr. Andy Alt receives the OVPR Faculty Achievement Award
    Dr. Andy Alt receives the OVPR Faculty Achievement Award
    Department News
    Faculty Promotions (effective September 1, 2023)
    Faculty Promotions (effective September 1, 2023) at the U-M Medical School Department of Pharmacology