Christine E Canman
Associate Professor of Pharmacology
[email protected]

Available to mentor
Christine E Canman
Associate Professor
  • Recent Publications
    • Recent Publications See All Publications
    • Presentation
      Academy of Educators: Synchronous vs. Asynchronous Lectures Panel
      Canman C, Tai A, Hortsch M. 2022 Nov 2;
    • Journal Article
      Which Holds the Key to BRCAness: Inability to Repair the Break, Protect the Fork, or Prevent the Gap?
      Canman CE. Cancer Res, 2021 Mar 1; 81 (5): 1214 - 1215. DOI:10.1158/0008-5472.CAN-20-4340
      PMID: 33822743
    • Journal Article
      Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer.
      Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA. Mol Cancer Ther, 2021 Feb; 20 (2): 263 - 273. DOI:10.1158/1535-7163.MCT-20-0365
      PMID: 33268569
    • Journal Article
      Replication Stress: An Achilles' Heel of Glioma Cancer Stem-like Cells.
      Morgan MA, Canman CE. Cancer Res, 2018 Dec 15; 78 (24): 6713 - 6716. DOI:10.1158/0008-5472.CAN-18-2439
      PMID: 30498082
    • Journal Article
      A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro.
      Fritzen R, Delbos F, De Smet A, Palancade B, Canman CE, Aoufouchi S, Weill J-C, Reynaud C-A, Storck S. DNA Repair (Amst), 2016 Oct; 46: 37 - 46. DOI:10.1016/j.dnarep.2016.07.002
      PMID: 27481099
    • Journal Article
      ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells.
      Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, Yu X, Canman CE, Ljungman M, Simeone DM. Cancer Res, 2014 Mar 15; 74 (6): 1778 - 1788. DOI:10.1158/0008-5472.CAN-13-2289
      PMID: 24469230
    • Journal Article
      PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer.
      Prensner JR, Chen W, Iyer MK, Cao Q, Ma T, Han S, Sahu A, Malik R, Wilder-Romans K, Navone N, Logothetis CJ, Araujo JC, Pisters LL, Tewari AK, Canman CE, Knudsen KE, Kitabayashi N, Rubin MA, Demichelis F, Lawrence TS, Chinnaiyan AM, Feng FY. Cancer Res, 2014 Mar 15; 74 (6): 1651 - 1660. DOI:10.1158/0008-5472.CAN-13-3159
      PMID: 24473064
    • Journal Article
      A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
      Inoue A, Kikuchi S, Hishiki A, Shao Y, Heath R, Evison BJ, Actis M, Canman CE, Hashimoto H, Fujii N. J Biol Chem, 2014 Mar 7; 289 (10): 7109 - 7120. DOI:10.1074/jbc.M113.520429
      PMID: 24474685