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Christine E. Canman, Ph.D.

Associate Professor of Pharmacology
Associate Director for Cancer Biology, Medical School

Office: 1301B MSRB 3

Lab: 1315 MSRB 3

Office: 734-764-7178 Lab: 734-647-1414

Biography

Dr. Canman received her B.S. degree in Microbiology from the University of Illinois in 1987 and Ph.D. degree in Pharmacology in 1992 from the University of Michigan. She then trained under the mentorship of Dr. Michael B. Kastan as a postdoctoral fellow at Johns Hopkins University from 1993 - 1998. There she investigated signaling pathways induced by ionizing radiation and mediated by the Ataxia Telangiectasia Mutated protein kinase. Dr. Canman then joined the faculty at St. Jude Children’s Research Hospital as an Assistant Member and continued her research in understanding signaling pathways related to the maintenance of genome stability and responses to ionizing radiation. From 2002-2004, Dr. Canman pursued a new career in Oncology Drug Discovery at Pfizer in Ann Arbor. There, she worked on projects related to the development of tyrosine kinase inhibitors for cancer treatment. In 2004, Dr. Canman became an Assistant Professor in the Department of Pharmacology at the University of Michigan where she continues to investigate cellular mechanisms that promote genome stability and resistance to standard chemotherapeutic agents. In 2012, she was promoted to Associate Professor with tenure.

Areas of Interest

How postreplication repair protects against genomic instability and influences the therapeutic response of cells treated with ionizing radiation or anti-cancer agents that target DNA.

Honors & Awards

First Place Junior Faculty Platform Presentation, Twelveth Annual Midwest DNA Repair
symposium, 2010
Glaxo-Wellcome Oncology Clinical Research Scholar Award, 1997
American Society of Hematology Fellowship Scholar Award, 1996
Poster award winner, Oncology Fellow Research Day, Johns Hopkins Oncology Center, 1995
American Association for Cancer Research Travel Award, 1995
NRSA fellowship award - Johns Hopkins Department of Pediatric Oncology, 1993
University of Michigan Cancer Research Fellowship, 1991
Lawrence Upjohn Fellowship, University of Michigan, 1988
Clinical Research Fellowship, University of Michigan, Department of Anesthesiology, 1987

Credentials

Education

Ph.D., Pharmacology, University of Michigan, 1993
BS, Microbiology, University of Illinois, Urbana, IL, 1987

Post-Doctoral Training

Postdoctoral fellow, Johns Hopkins University, 1993-1998

Web Sites