Recent PSTP Alumni

"Multi-Objective Engineering of Therapeutic Antibodies"

"Rapidly Translational Drug Discovery Using High Content Imaging: Applications to Non-Alcoholic Fatty Liver Disease and the COVID-19 Pandemic"

"The hERG1 PAS Domain: An Anti-arrhythmic Drug Target and Master Regulator of IKr"

"Delineating the Specificity of Cannabinoid Effects by Investigating Cannabinoid Receptor-1 Trafficking and Signaling"

"Regulation of Chromaffin Cell Exocytosis via Endogenously Secreted Signaling Molecules Acetylcholine and PACAP"

"Targeting DNA Damage, Apoptosis, and the Cell Cycle for the Radiosensitization of Aggressive Forms of Breast Cancer"

"Elucidation of DNA-Binding and Dimerization Activities of the Master Virulence Transcription Factor, VirF, From Shigella flexneri to Aid in Virulence-Targeted Inhibitor Design for Treatment of Shigellosis"

"Mechanistic Analysis and Quantification of Clofazimine"

"Structural and Functional Analysis of Human Dicer"

"The Role of Voltage-Gated Sodium Channel Gene Scn1b in the developing pediatric heart"

"Ankyrin-B is Lipid-Modified by S-Palmitoylation to Promote Dendritic Membrane Scaffolding of Voltage Gated Sodium Channel Nav1.2 in Neurons"

"Targeting the Hsp90 Molecular Chaperone and Resistant Pathways in BRAF-mutant Melanoma"

"Droplet Microfluidics Coupled to Mass Spectrometry for Pharmacological Applications"

"Inhibition of Nucleotide and One-Carbon Metabolism for the Treatment of Cancer"

"Pharmacology of Hsp70 Activation"

"Synthesis of a Monoamine Oxidase B Selective PET Tracer"

"Personalized immunotherapy for Glioblastoma multiforme (GBM) using neoantigen-loaded synthetic high-density (sHDL) lipoprotein nanodisc vaccines"

"Mechanisms and Modeling of the Intestinal Absorption, Activation, and Systemic Availability of Gemcitabine and a Gemcitabine Prodrug for Oral Administration"

"Effects of Protein Kinase CBeta Inhibition on Drug- Taking"

"Structure-Based Design of IKKe and TBK1"

"Prodrug Targeting and Activitation Strategy for Improving the Oral Absorption of Gemcitabine"

"Targeting the eiF4E-4E-BP2 Protein-Protein Interaction in Human Disease"

"Exploration of Control Mechanisms for Mu-Delta Opiod Receptor Signaling Using Opiod Peptides and Peptidomimetics"

"Targeting KRAS Signaling to Treat GI Cancers"

"Development of Inhibitors of SUMO-Specific Protease"

"Conformation Selective Kinase Inhibitors"

"Discovery and Development of Small Molecule Probes for the SUMO Protease SENP1, a Novel Target for Advanced Prostate Cancer Therapy"

"Kinetic Analysis of Human DNA Ligase III"

"Drug Discovery for Rifampin- Resistant Mycobacterium Tuberculosis"

"Studies of Cytochrome P450 17A1 (CYP17A1) Genetic Polymorphism"

"Tamoxifen Analogues as Therapeutics for Psychostimulant Addiction"

"SRole of Regulator of G-Protein Signaling Proteins in Serotonin and Opioid Mediated Behaviors"

"Rhodacyanines Inhibit Hsp70 Protein-Protein Interactions and Stabilize Substrate Bound Protein Complexes"

"Novel Antibiotic Discovery Targeting VirF a Virulence- Regulating Transcription Factor"

"The Role of Arrestin in Membrane Structure and the Mechanism of Activation by the Beta2-Adrenergic Receptor"

"Nanotheranostics for Cancer Imaging and Drug Delivery"

"The Role of Epigenetic Silencing and Ion Channel Suppression in Cancer Cell Survival"

"Development of Adjuvant- Loaded PLGA Microspheres for Delivery of Vaccine Antigen"

"Development of New Strategies for Intramolecular Glycosylation"