Research Assistant Professor
Pharmacology
[email protected]
Available to mentor
Jess Anand
Research Assistant Professor
-
PhDUniversity of Michigan, Ann Arbor, 2013
-
MSUniversity of Michigan, Ann Arbor, 2009
-
BABarnard College, Columbia University, New York, 2007
Medicinal chemistry; structure activity relationships, opioids; CNS disorders; substance use disorder
https://sites.google.com/view/anand-lab/home
-
Disney A, Olson KM, Shafer AM, Moore SC, Anand JP, Traynor JR, Husbands SM. ACS Chem Neurosci, 2022 Nov 2; 13 (21): 3108 - 3117.Journal ArticleOpioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose.
DOI:10.1021/acschemneuro.2c00464 PMID: 36223082 -
2021 Feb 1;PresentationSilk Purses from Sow's Ears: Designing Safer Pain Killers.
-
Henry S, Anand JP, Brinkel AC, McMillan DM, Twarozynski JJ, Loo CE, Traynor JR, Mosberg HI. ACS Chem Neurosci, 2021 Jan 6; 12 (1): 216 - 233.Journal ArticleSAR Matrices Enable Discovery of Mixed Efficacy μ-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore.
DOI:10.1021/acschemneuro.0c00693 PMID: 33346631 -
Hassanien SH, Bassman JR, Perrien Naccarato CM, Twarozynski JJ, Traynor JR, Iula DM, Anand JP. Drug Test Anal, 2020 Aug; 12 (8): 1212 - 1221.Journal ArticleIn vitro pharmacology of fentanyl analogs at the human mu opioid receptor and their spectroscopic analysis.
DOI:10.1002/dta.2822 PMID: 32415719 -
Henry S, Anand JP, Twarozynski JJ, Brinkel AC, Pogozheva ID, Sears BF, Jutkiewicz EM, Traynor JR, Mosberg HI. J Med Chem, 2020 Feb 27; 63 (4): 1671 - 1683.Journal ArticleAromatic-Amine Pendants Produce Highly Potent and Efficacious Mixed Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Peptidomimetics with Enhanced Metabolic Stability.
DOI:10.1021/acs.jmedchem.9b01818 PMID: 31986033 -
Montgomery D, Anand JP, Baber MA, Twarozynski JJ, Hartman JG, Delong LJ, Traynor JR, Mosberg HI. Molecules, 2019 Nov 26; 24 (23):Journal ArticleStructure-Activity Relationships of 7-Substituted Dimethyltyrosine-Tetrahydroisoquinoline Opioid Peptidomimetics.
DOI:10.3390/molecules24234302 PMID: 31779072 -
Montgomery D, Anand JP, Griggs NW, Fernandez TJ, Hartman JG, Sánchez-Santiago AA, Pogozheva ID, Traynor JR, Mosberg HI. ACS Chem Neurosci, 2019 Aug 21; 10 (8): 3682 - 3689.Journal ArticleNovel Dimethyltyrosine-Tetrahydroisoquinoline Peptidomimetics with Aromatic Tetrahydroisoquinoline Substitutions Show in Vitro Kappa and Mu Opioid Receptor Agonism.
DOI:10.1021/acschemneuro.9b00250 PMID: 31199621 -
Nastase AF, Anand JP, Bender AM, Montgomery D, Griggs NW, Fernandez TJ, Jutkiewicz EM, Traynor JR, Mosberg HI. J Med Chem, 2019 Apr 25; 62 (8): 4193 - 4203.Journal ArticleDual Pharmacophores Explored via Structure-Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design.
DOI:10.1021/acs.jmedchem.9b00378 PMID: 30916966
Department News
Dr. Jessica Anand receives "Making a Difference" award in the Department of Pharmacology at the University of Michigan Medical School.