Michael Holinstat, Ph.D.

Associate Professor of Pharmacology
Associate Professor of Internal Medicine, Division of Cardiovascular Medicine
Associate Professor of Vascular Surgery
Director, TL1 MS program in clinical research (MSCR)
Director, Platelet Physiology and Pharmacology Core

Office: 2220D MSRB 3

Lab: 2240 MSRB 3

Office: 734-764-4046 Lab: 734-763-8824


Michael Holinstat received his Ph.D. in Pharmacology from the University of Illinois at Chicago and postdoctoral training at Vanderbilt University. His research focuses on identifying novel approaches to anti-platelet therapy with a special emphasis on regulation of platelets through the lipoxygenase pathway leading to a number of oxidized fatty acids which may play a central role in regulating unwanted platelet activation. Additionally, the lab studies regulation of platelet signaling through PAR1 and PAR4.

Areas of Interest

 Thrombosis, signal transduction, Pharmacology, Hematology.

Honors & Awards

Elected Fellow of the American Heart Association (FAHA), 2014
Young Investigator Award in Structure and Function (Eicosanoid Research Foundation), 2013
Kenneth M. Brinkhous Young Investigator Prize in Thrombosis (American Heart
Association), 2012
ISTH New Investigator Travel Award (XXIII Congress of the ISTH, Kyoto, Japan), 2011
ASPET Board of Trustee Travel Award (National ASPET meeting at FASEB; 2009), 2009
Postdoctoral Travel Award (National ASBMB Meeting at FASEB), 2008
ASPET Postdoctoral Scientist Award (Division of Molecular Pharmacology), 2008
Recipient of the LRP from NIH, 2007
Postdoctoral Travel Award (National ASBMB Meeting at FASEB), 2007
Young Scientist Travel Award (National ASPET meeting at FASEB), 2006
Albert and Doris Woltjien Scholar in Pharmacology, 2003
ASPET Best Paper award in molecular pharmacology (FASEB meeting), 2002
Pre-Doctoral Travel award (National ASPET meeting at FASEB), 2002
Travel award to present work at annual SFN meeting, 2000
Travel award to present work at annual ARO meeting, 1999



Ph.D., Pharmacology, University of Illinois at Chicago, 2004
MS, Biological Sciences, University of Illinois at Chicago, 2000
BS, Biology, Southern Connecticut State University, 1995

Post-Doctoral Training

Postdoctoral Research Fellow, Vanderbilt University Medical Center, Nashville, 2004-2008

Published Articles or Reviews

Web Sites