RESEARCH FOCUS: Sarcoma tumor biology.
Faculty
Laurence Baker, Professor Emeritus
J. Chad Brenner, Assistant Professor
RESEARCH FOCUS: Bioinformatics, high-throughput siRNA/drug screening and functional genomics approaches to understand cancer biology and discover novel small molecule therapeutics.
Matthew Brody, Assistant Professor
RESEARCH FOCUS: Molecular Cardiovascular Biology.
Yuqing Eugene Chen, Professor
RESEARCH FOCUS: Cardiovascular medicine, molecular basis of diabetes/obesity-induced cardiovascular diseases and stroke.
Michelle Hastings, Professor
Research Focus: RNA therapeutics, RNA splicing, antisense oligonucleotides, rare disease, genetics, inflammation, Usher syndrome, cystic fibrosis, Batten disease, Alzheimer’s and Parkinson’s disease
Michael Holinstat, Associate Professor
RESEARCH FOCUS: Platelets, Thrombosis, Hemostasis, Clotting, Lipids, Lipoxygenase, Clinical research, Translational research, 12-LOX.
Lori Isom, Professor
RESEARCH FOCUS: Mechanisms of epileptic encephalopathy and cardiac arrhythmias linked to mutations in voltage-gated sodium channel genes; mechanisms of sudden unexpected death in epilepsy (SUDEP); ion channel structure and function; transgenic mouse models of neurological and cardiac disease; patient-derived induced pluripotent stem cell neurons and cardiac myocytes.
Paul Jenkins, Assistant Professor
RESEARCH FOCUS: Cellular and molecular neuroscience, Neuropsychiatric disease mechanisms, Bipolar disorder, Protein trafficking, Palmitoylation, Epithelial cell biology,Membrane structure, Mouse models, Electrophysiology.
David Jones, Assistant Professor
RESEARCH FOCUS: Voltage-gated potassium channel, hERG, cardiac physiology and pathophysiology.
Yoichi Osawa, Professor
RESEARCH FOCUS: Hsp90 and Hsp70 chaperones, ubiquitination, protein quality control, nitric oxide synthases, steroid receptors, cytochrome P450.
Manojkumar Puthenveedu, Associate Professor
RESEARCH FOCUS: GPCR trafficking and signaling, opioid, drug addiction.
James Rae, Associate Professor
RESEARCH FOCUS: Predicting response to breast cancer therapies by way of pharmacogenetic, pharmacogenomic, drug metabolism and candidate gene pathway analyses.
Peter J. H. Scott, Associate Professor
RESEARCH FOCUS: Adaptation of state-of-the-art organic chemistry techniques (including SPOS) for radiochemical applications, Microwave mediated radiochemistry, Development of multi-modality biomarkers for PET-MRI.
Judith Sebolt-Leopold, Research Professor
RESEARCH FOCUS: Drug discovery, molecular pharmacology, assay development, and biomarker validation.
James A. Shayman, Professor
RESEARCH FOCUS: Lysosomal storage diseases and the biochemistry, cellular biology and pharmacology of sphingolipids.
Gregory Tall, Associate Professor
RESEARCH FOCUS: Heterotrimeric G protein Signaling, G protein folding chaperones, Mechanisms of Adhesion GPCR action, Somatic G protein disease mutations, GNAQ/11-driven uveal melanoma, High throughput screening and small molecule probe discovery.
Yukun Yuan, Research Assistant Professor
RESEARCH FOCUS: Neurotoxicology, neuropharmacology/neurophysiology and neurological disorders.
Haoming Zhang, Research Associate Professor
RESEARCH FOCUS: Drug metabolism and discovery, cytochrome P450 structure and function, Chaperone Hsp 70.