Position available immediately in the laboratory of Dr. Les Satin in the Brehm Diabetes Center/Department of Pharmacology for a qualified Ph.D., M.D. or M.D./Ph.D. scientist to carry out live cell imaging and molecular biology experiments investigating the cellular and molecular signaling mechanisms underlying pulsatile insulin secretion, cell imaging, and electrophysiology using mouse and human pancreatic beta cells. Candidates with specific experience studying insulin exocytosis, hormone oscillations, mitochondrial function or calcium signaling in cells will be preferred, although this is not mandatory. Experience with molecular biological approaches and genetics will also be needed.
Two Postdoctoral Positions Available:
Postdoctoral Position 1
Postdoctoral Position 2
NIH-Funded Postdoctoral Position Available.
Position available immediately in the laboratory of Dr. Les Satin in the Brehm Diabetes Center/Department of Pharmacology for a qualified Ph.D., M.D. or M.D./Ph.D. scientist to carry out live cell imaging and molecular biology experiments investigating the role of endoplasmic reticulum-mitochondrial communication in human beta cell demise in type 1 diabetes. Research in this project will involve close collaboration with other beta cell laboratories in the Brehm Center and will be highly interdisciplinary. Candidates with specific experience studying endoplasmic reticulum, mitochondria or their cross-talk and the use of fluorescence microscopy approaches will be preferred, although such experience is not mandatory.
The Brehm Center is a leading biomedical research center that houses different laboratories focused on the use of state of the art approaches to studying diabetes, obesity and metabolism. The Brehm Center is a highly interactive and collaborative research and training environment that includes state of the art cores in metabolomics, animal phenotyping, optical imaging and is adjacent to top flight University of Michigan resources including viral vector, sequencing, transgenic mouse, genetics, and live cell and small animal imaging core facilities.
Well-qualified individuals will possess an Ph.D. or M.D. degree and experience in cell and molecular biology including advanced live cell optical limaging approaches, cell culture, adenovirus mediated gene expression, western blotting, cloning, knockout mouse models, PCR and related techniques. Individuals with additional experience studying pancreatic islet cells, biophysics, cell calcium signaling, protein trafficking, biological oscillations and/or electrophysiology would be especially qualified for this post.
Interested individuals should submit a letter of introduction, a statement indicating their research experience, and a current CV, and should arrange for 3 letters of recommendation to be sent to Dr. Leslie S. Satin at [email protected].