Michelle Kim

Michelle Kim, MD

Assistant Professor
Director of Medical Student Education
Co-Chair of Cancer Center Neuro-Oncology Clinical Research Team

UH B2 C490

1500 E Medical Center Dr

Ann Arbor, MI 48109-5010

734-936-4300

Clinical Contacts

734-936-4300

Administrative Contact

Samantha Harbarcuk 734-647-3142

Biography

As Co-Chair of the Cancer Center Neuro-Oncology Clinical Research Team and Principal Investigator of multiple clinical trials, Dr. Kim is a leader in brain tumor clinical research and involved with efforts institutionally, regionally and nationally. Her primary focus is on the use of advanced imaging modalities as a biomarker to understand the biologic basis of tumor response and treatment resistance to radiation therapy, in order to individually adapt radiation treatment and improve outcome in patients with malignant gliomas. She is also interested in the evaluation of advanced imaging techniques to predict long-term toxicity and response in patients with low grade gliomas and brain metastases. Dr. Kim is principal investigator of several ongoing clinical trials evaluating the use of a newly developed advanced MR imaging technique for the intensification of radiation treatment in patients with newly diagnosed glioblastoma, and the evaluation of a novel radiosensitizer (RRx-001) in combination with radiotherapy in patients with brain metastases.

Areas of Interest

  • Prediction of treatment response and adaptive individualization of radiation treatment using advanced imaging modalities in malignant gliomas
  • Evaluation of novel, targeted radiosensitizers in patients with brain metastases
  • Clinical trials for brain metastases and adult gliomas

Clinical Interests

  • Adult central nervous system tumors of the brain and spine
  • Stereotactic radiosurgery
  • Stereotactic body radiation therapy

Honors & Awards

2012   American Association for Women Radiologists Eleanor Montague Distinguished Resident Award in Radiation Oncology
2012   Radiation Therapy Oncology Group/American College of Radiology Clinical Research Fellowship Awardee
2011   American Association for Women Radiologists Research and Education Foundation Member-in-Training Award
2011   American Society of Clinical Oncology Cancer Foundation Merit Award
2010   Korean Society for Radiation Oncology Travel Award
2007   Alpha Omega Alpha
2004-2006   Ohio Board of Regents Graduate/Professional Fellowship
2004-2008   Case School of Medicine Dean’s Scholarship
2004   George T. Hunt Award for leadership, scholarship and service
2003   American Association for Cancer Research Thomas J. Bardos Science Education Award
2003   Joseph Skigin Memorial Award
2003   Phi Beta Kappa
2000-2004   Case Undergraduate Trustee’s Scholarship

Credentials

  • BA, Case Western Reserve University, 2004
  • MD, Case Western Reserve University, 2008
  • Internal Medicine Internship, MetroHealth Medical Center, Cleveland, OH, 2009
  • Residency, Radiation Oncology, MD Anderson Cancer Center, Houston, TX, 2013
  • Board Certification: Radiation Oncology, 2014

Grants

(PI: Kim),  07/2013-01/2018 EpicentRx, Inc.: A phase I dose-escalation study of RRx-001 in combination with whole brain radiation in subjects with brain metastases, Role: Principal Investigator.

(PI: Kim), 07/15-07/2017, University of Michigan Department of Radiology Nuclear Medicine Seed Grant: Phase II Study of High Dose Radiotherapy and Concurrent Temozolomide Using Biologically-based Target Volume Definition in Patients with Newly Diagnosed Glioblastoma, Role: Principal Investigator.

(PI: Kim), 07/2015-07/2017, University of Michigan Clinical/Translation Resource Allocation Committee Grant: Phase II Study of High Dose Radiotherapy and Concurrent Temozolomide Using Biologically-based Target Volume Definition in Patients with Newly Diagnosed Glioblastoma, Role: Principal Investigator.

(PI: Kim), 07/2015-07/201, Michigan Memorial Phoenix Project: Phase II Study of High Dose Radiotherapy and Concurrent Temozolomide Using Biologically-based Target Volume Definition in Patients with Newly Diagnosed Glioblastoma, Role: Principal Investigator.

(PI: Kim), 06/2016-06/2017, Continuing Medical Education Innovation Grant: Engaging Academic and Community Partners: A Tumor Board-based Approach to Enhancing the Multidisciplinary Care of Patients with Brain Metastases and Leptomeningeal Disease, Role: Principal Investigator.

Published Articles or Reviews

Selected from 16 publications

  • Kim MM, Parolia A, Dunphy M, Venneti S. Non-invasive metabolic imaging of brain tumours in the era of precision medicine. Nat Rev Clin Onc, 13:725-39, 2016.
  • Albert NL, Weller M, Suchorska B, Galldiks N, Soffietti R, Kim MM, la Fougere C, Pope W, Law I, Arbizu J, Chamberlain M, Vogelbaum M, Ellingson BM, Tonn JC. Response Assessment in Neuro-Oncology working group and European Association for Neuro-oncology recommendations for the clinical use of PET imaging in gliomas. Neuro-Oncology,18(9): 1199-1208, 2016.
  • Zhu T, Chapman C, Tsien C, Kim MM, Spratt D, Lawrence TS, Cao Y. Effect of the Maximum Dose on White Matter Fiber Bundles Utilizing Longitudinal Diffusion Tensor Imaging. Int J Radiat Oncol Biol Phys, 96(3):696-705, 2016.
  • Kim MM, Camelo-Piragua S, Betz B, Cao Y, Junck L, Mammoser A, Schipper M, Tao Y, Kim CJ, Heth J, Sagher O, Lawrence TS, Tsien CI. Gemcitabine plus radiation therapy for high grade glioma: long-term results of a phase I dose-escalation study. Int J Radiat Oncol Biol Phys, 94(2):305-11, 2016
  • Kim MM, Lawrence TS, Cao Y. Advances in magnetic resonance and positron emission tomography imaging: assessing Response in the Treatment of Low Grade Glioma. Seminars in Radiation Oncology, 25(3):172-180, 2015.
Locations

1500 E Medical Center Dr
Ann Arbor, MI 48109-5010

734-936-4320