Cancer Biology Laboratories

The Radiation and Cancer Biology Division in the Department of Radiation Oncology of the University of Michigan was established in 1995. Overall goals of this division are to understand the mechanism of cellular response to radiation and to identify and target the molecules and signaling pathways that are responsible to radioresistance in human cancer. The ultimate goal is to improve current radiation therapy alone and in combination with chemotherapy for the treatment of cancer patients.

The projects undertaken by Faculty range from early target identification, to mechanistic study of signaling molecules, and to application of laboratory knowledge in clinic radiotherapy. Many state-of-art technologies are being used, including nanotechnology, transgenic and knockout mice, high throughput screening of siRNA library, and functional imaging.