Ronald D. Chervin, MD, MS

Dr. Chervin’s research, funded by the NIH since 1997, has addressed a wide range of challenges and opportunities in sleep medicine.  Particular focus has centered on sleep-disordered breathing across the lifespan, sleepiness, subjective and objective assessment techniques, biomedical innovation, and neurobehavioral consequences of childhood sleep disorders.  Dr. Chervin has collaborated on many research projects focused on the intersection of sleep and neurologic disease, including stroke, multiple sclerosis, neurodegenerative disease, movement disorders, neuropathy, epilepsy, and neonatal neurologic critical care.  Other collaborations have advanced knowledge of the intersection between sleep and medical conditions such as pregnancy and asthma. 

Dr. Chervin has published more than 170 peer-reviewed manuscripts.  He has mentored many residents, fellows, and junior faculty in the pursuit of their own sleep and neurology research aims, and has been recognized by institutional awards for his clinical research, team science, and research mentorship.  Dr. Chervin serves as the Innovation Chief for the Department of Neurology and its participation in the Fast Forward Medical Innovation (FFMI) program at the University of Michigan.  He has served as a member of the boards of directors for the American Academy of Sleep Medicine, the American Sleep Medicine Foundation, the Associated Professional Sleep Societies, the Sleep Research Society, and the International Pediatric Sleep Association.  He has been as a member of the NHLBI Sleep Disorders Research Advisory Board, and the advisory board for Sweet Dreamzzz, a non-profit that brings innovative sleep education to children in low socioeconomic areas.  He has also served as a Deputy Editor for Sleep, and on the editorial boards for Journal of Clinical Sleep Medicine and Sleep Medicine.

Publications authored or co-authored by Dr. Chervin are listed at:

http://www.ncbi.nlm.nih.gov/sites/myncbi/ronald.chervin.1/bibliograpahy/44371050/public/?sort=date&direction=ascending

Examples of grants for which Dr. Chervin has served as the Principal Investigator (PI), Co-PI, Site PI, or Primary Mentor include:

Sleep-Disordered Breathing and CPAP after Adenotonsillectomy in Children

The goal is to assess neurobehavioral benefits of continuous positive airway pressure for residual sleep apnea after adenotonsillectomy, and to determine which children are most likely to benefit.

Role: PI

Funding:  R01 HL105999  

Impact of Treatment of Mild Sleep-Disordered Breathing on Children’s Health

The goal of this multicenter randomized controlled trial is to assess whether adenotonsillectomy for primary snoring, in the absence of obstructive sleep apnea, improves neurobehavioral and other key outcomes.

Role: Site PI for subcontract to University of Pennsylvania

Funding:  U01 HL125295  Marcus (PI)  

Multi-Institutional Training in Genetic/Genomic Approaches to Sleep Disorders

This grant, administered through the University of Pennsylvania for training programs at Michigan, Stanford, and Hopkins, seeks to train investigators who can advance research at the interface of sleep and genetics.

Role: Site PI (multi-PI training grant)

Funding:  T32 HL110952  Pack, Chervin, Mignot, Polotsky (PIs)                                                         

Increasing Sleep Health Literacy in Head Start: A Social-Ecological Approach

The goal is to develop and demonstrate efficacy of new programs that will identify and address common and consequential sleep problems among vulnerable preschool children enrolled in Head Start programs.

Role: Site PI for subcontract to Einstein

Funding:  R01 HD082129  Bonuck (PI)   

Sleep-Disordered Breathing and PAP in Perinatal Depression

The goal of this mentored career award is to assess the role of obstructive sleep apnea and its treatment in the exacerbation and improvement, respectively, of perinatal depression.

Role:  Primary mentor

Funding:  K23 HL122461  Swanson (PI)  

Mechanical airway support device to treat obstructive sleep disordered breathing

The main goal of this SBIR award to MC3, Inc. was to develop a mechanical continuous positive airway pressure device that is inexpensive, requires no electricity, functions silently, and is highly portable.

Role:  PI (multi-PI SBIR award)

Funding:  NIH / NHLBI  R34 HL117421 Wong and Chervin (PIs)   

Use of PAP in women with pre-eclampsia

The main goal of this career development award was to assess maternal and fetal benefit derived from treatment of sleep-disordered breathing among women with hypertensive disorders of pregnancy.

Role:  Primary mentor

Funding:  NIH / NHLBI  K23 HL095739  O’Brien (PI)     

PET Study of Biochemistry and Metabolism of the CNS: Subproject 3, Serotonin and Sleep-Disordered Breathing in Parkinson Disease

The main goal was to assess whether serotonergic abnormalities in patients with Parkinson Disease may contribute to sleep-disordered breathing

Role:  Co-PI for Subproject

Funding:  NIH / NINDS  P01 NS015655 Frey (PI); Albin (Subproject PI)   

A Randomized Controlled Study of Adenotonsillectomy for Children

This multi-center childhood adenotonsillectomy (“CHAT”) trial assessed neurobehavioral effects of the procedure in children with obstructive sleep apnea.

Role:  Site PI

Funding:  U01 HL083219 Ellenberg (PI)
NIH/ NHLBI through subcontract with University of Pennsylvania