Shuang Wei, PhD, is a research faculty member in the Section of General Surgery, Division of Surgery Oncology, at the University of Michigan Health Systems. Dr. Wei received her Bachelor and Masters of Science at Tongji Medical School in China in 1991 and 1994 respectively. Dr. Wei received her PhD degree at the University of Paris, France, in 1998. She went on to do postdoctoral training at Baylor Institute for Immunology Research in Texas from 1999 to 2001. From 2001 to 2003, Dr. Wei did her postdoctoral training at Tulane University Health Science Center, in New Orleans, Louisiana. In January 2004, Dr. Wei joined the faculty at Tulane School of Medicine as a Research Instructor of Medicine. In April of 2006, Dr. Wei joined the faculty of the Section of General Surgery, University of Michigan Health Systems, as a Research Investigator.
Dr. Wei's research interest/focus is to investigate how tumor specific immunity is established in vivo and in vitro in human and mouse models, how tumor develops immune suppressive mechanisms and how novel therapeutic strategies can be established to subvert tumor immunosuppression. Dr. Wei and colleagues recently observed that antigen presenting cell subsets were recruited by tumor derived chemokines into tumor environment, and induced suppressive regulatory T cells. Several subsets of regulatory T cells have now been described in the literature. Thus, Dr. Wei's current research particularly focuses on defining the role of regulatory T cells and chemokines/chemokine receptors in tumor immuno-pathogenesis.