The review was published in the Journal's January edition.
"The human bladder has two functions—to store and empty urine. Coordination and transition between these functions requires synergy among the detrusor muscle, urinary sphincters, and the central nervous system. When the central neurologic pathways controlling urine storage and emptying are disrupted by injury, inflammation, degenerative process or congenital malformation, the urinary sphincters and detrusor can lose coordination. If the detrusor muscle contracts while the sphincter is activated, bladder outlet obstruction occurs. Detrusor sphincter dyssynergia (DSD) is the urodynamic description of this neurologically induced bladder outlet obstruction."