Jeffrey Horowitz, M.D.

Associate Professor, Department of Internal Medicine
Pulmonary & Critical Care Medicine
6303 MSRB III/SPC 5642
1150 W. Medical Center Dr.
Ann Arbor, MI  48109-5642
Phone: 734-936-5010

Administrative Contact

Cat Meyer 734-936-5010

Areas of Interest

My research program has been focused on the mechanisms regulating mesenchymal cell survival and apoptosis in wound repair and fibrosis. Specifically, we have shown that soluble pro-fibrotic mediators promote myofibroblast resistance to a variety of apoptotic stimuli, and are working to better understand the signaling mechanisms involved. Included in this focus is the investigation of the mechanisms by which matrix interactions and the biomechanical microenvironment regulate mesenchymal cell susceptibility to apoptotic stimuli.

Clinically, I am a general pulmonologist with an interest in interstitial lung diseases, including idiopathic pulmonary fibrosis. Additional interests include the evaluation of lung nodules, including the diagnosis and staging evaluation of potential lung cancers, and the treatment of obstructive lung diseases such as asthma and COPD.

A profile is available at the U of M Health site.



M.D., 1998, Rush Medical College


1998-2001, Rush Presbyterian St.-Luke's Medical Center


Pulmonary And Critical Care Medicine, 2004, University of Michigan


2001, Internal Medicine 2003, Pulmonary Medicine 2004, Critical Care Medicine

Faculty Appointment Date


Published Articles via PubMed