In 2023 I received a B.S. in Molecular, Cellular, and Developmental Biology from the University of Michigan. I worked in the Yanzhuang Wang lab under Dr. Sarah Bui, where I worked on elucidating p53 as a novel transcription factor for the Golgi resident galactosyltransferase B4GALT1. I am currently interested in the metabolic effects of endoplasmic reticulum-mitochondria contact sites on tumor biology, specifically looking at the bidirectional effects of altered lipid metabolism on these contacts and vice versa.
Biography
Research Interests
Organelle biology, tumor metabolism, endoplasmic reticulum-mitochondria contact sites, lipid homeostasis.
Techniques Used
Live and fixed cell confocal fluorescent microscopy, molecular and cellular biology techniques, flow cytometry, ImageJ, FloJo, Microsoft office suite, adobe illustrator
Abstracts
Oral Presentation: Stark, D., Chen, B., Liu, T., Singhal, R., Lyssiotis, C., and Shah, Y. “Stearoyl-CoA Desaturase 1 (SCD) is Required for Endoplasmic Reticulum-Mitochondria Membrane Contact Site (ERMCS) Formation and Dynamics in Cancer,” University of Michigan Doctoral Program in Cancer Biology 11th Annual Retreat, Fox Hills Golf & Banquet Center, Plymouth, MI. 09/11/2024
Poster Presentation: Stark, D., Chen, B., Liu, T., Singhal, R., Lyssiotis, C., and Shah, Y. “Stearoyl-CoA Desaturase 1 (SCD) is Required for Endoplasmic Reticulum-Mitochondria Membrane Contact Site (ERMCS) Formation and Dynamics in Cancer,” • American Society for Cell Biology (ASCB) Conference Cell Bio 2024, San Diego, CA. 12/14/2024-12/18/2024 • University of Michigan Program in Biomedical Sciences (PIBS) 25th Anniversary Celebration, Ann Arbor, MI. 10/2/2024
Poster Presentation, Stark, D., Bui, S., Houmani, A., Liou, W., Li, J., and Wang, Y. “Identifying Golgi glycosyltransferase B4GALT1 as a p53-responsive gene in lung adenocarcinoma,” Undergraduate Research Symposium, University of Michigan, Ann Arbor, MI. 04/08/2022 • American Society for Cell Biology (ASCB) Conference Cell Bio 2022, Washington, D.C. 12/05/2022 • Undergraduate Research Symposium, University of Michigan, Ann Arbor, MI. 04/08/2022
Awards
UM LSA Program in Biology Directors Award
Benard Maas Fellow Cellular
Biotechnology Training Program (CBTP) NIH T32 Trainee
Publications
Student Roles
Cancer Biology Social Co-Chair, 2024
PACCAR Director of Professional Development: 08/2024-12/2024
Cancer Bio Mentor
Costas Lyssiotis, Ph.D.
Director, Doctoral Program in Cancer Biology
Maisel Research Professor of Oncology
Yatrik Shah, Ph.D.
Professor of Molecular & Integrative Physiology
Professor of Internal Medicine