In 2023 I received a B.S. in Molecular, Cellular, and Developmental Biology from the University of Michigan. I worked in the Yanzhuang Wang lab under Dr. Sarah Bui, where I worked on elucidating p53 as a novel transcription factor for the Golgi resident galactosyltransferase B4GALT1. I worked to characterize this relationship in a Lung Adenocarcinoma model, describing how TP53 null cancers under express B4GALT1, leading to an aberrant glycosylation phenotype. I also served as an Undergraduate Teaching Assistant within the Program in Biology at UM. Outside of lab, I love to play and watch both golf and hockey, exercise, and spend time with family, especially our dog Gus :)
Biography
Research Interests
I am broadly interested in the molecular complexity of the tumor microenvironment (TME) in solid cancers, including how tumors rewire their metabolism to utilize nutrients available in the TME, cell communication and immune landscape within the TME, and how new understandings of these concepts can be leverage for novel cancer therapeutics.
Techniques Used
Dual-luciferase assays, molecular cloning, immunofluorescence, Western blot
Abstracts
“Identifying Golgi glycosyltransferase B4GALT1 as a p53-responsive gene in lung cancer,” Bui, S., Stark, D., Houmani, A., and Wang, Y. American Society for Cell Biology (ASCB) Conference Cell Bio 2022, Washington D.C.
Awards
2023 Program in Biology Director's Award
University of Michigan Benard L. Maas Fellowship