Discovering genetic and environmental risk factors for amyotrophic lateral sclerosis
Dr. Stephen Goutman’s clinical and research expertise is focused on Amyotrophic lateral sclerosis (ALS), a progressive, fatal neurodegenerative disease with limited treatment options. Dr. Goutman is the Director of the University of Michigan Pranger ALS Clinic, an ALS Association Certified Center of Excellence, where a team of providers deliver comprehensive and compassionate care to persons with ALS and their families.
Inspired by his patients, Dr. Goutman’s research focuses on identifying new mechanisms and therapies for ALS. His research expertise is focused on understanding the genetic and environmental interactions that alter susceptibility to ALS, especially in the State of Michigan which has some of the highest rate of ALS in the country. With funding from the National Institutes of Health, the Centers for Disease Control and Prevention, and the ALS Association, he is discovering environmental risk factors associated with the onset and progression of ALS by collecting epidemiologic exposure surveys and biofluids from individuals with and without ALS. His research shows a link between ALS and pesticides, and his recent article on this work received widespread attention, as this important finding may help solve the mystery of ALS. Dr. Goutman also collaborates with teams of scientists to identify the immune system’s role in ALS and find new drugs that can address these changes in the immune system.
Dr. Goutman serves as site principal investigator of several multi-site clinical trials focused on identifying new ALS treatments. He is an active participant with the Northeast ALS Consortium (NEALS) and has close to a decade of experience leading ALS clinical trials at University of Michigan.
- BS, Neuroscience, Johns Hopkins University, 2002
- MD, University of Chicago Pritzker School of Medicine, 2007
- Neurology Residency & Neuromuscular Fellowship, Cleveland Clinic, 2011-12
- MS, Clinical Research Design and Statistical Analysis, University of Michigan, 2015
Honors & Awards
- Young Investigator Award, World Federation of Neurology Research Group on Motor Neuron Diseases
Dr. Goutman will use the three-year ALS Association grant to consider how genetic factors and environmental pollutants jointly affect ALS development and progression in patients.
Dr. Stephen Goutman reviewed his recent ALS research on<br> Michigan Radio’s Stateside program. His latest findings<br> examined how environmental toxins impact ALS progression.
Dr. Stephen Goutman, clinical director of the ALS Center of Excellence, threw out the ceremonial first pitch at the University of Michigan baseball team's inaugural ALS Awareness Game on May 7.
The Detroit Free Press featured Dr. Eva Feldman, Dr. Stephen Goutman, patient Rob Cotton, and Lisa Cotton in its story on the role of pesticides and pollutants in ALS.
A new study helps determine the role of pesticides and pollutants during the course of the progressive neurodegenerative disease that has no cure.